Gao FB - Search Results

1

Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules.

Markmiller S, Soltanieh S, Server KL, Mak R, Jin W, Fang MY, Luo EC, Krach F, Yang D, Sen A, Fulzele A, Wozniak JM, Gonzalez DJ, Kankel MW, Gao FB, Bennett EJ, Lécuyer E, Yeo GW. Markmiller S, et al. Among authors: gao fb. Cell. 2018 Jan 25;172(3):590-604.e13. doi: 10.1016/j.cell.2017.12.032. Cell. 2018. PMID: 29373831 Free PMC article.

2

Frontotemporal dementia and amyotrophic lateral sclerosis-associated disease protein TDP-43 promotes dendritic branching.

Lu Y, Ferris J, Gao FB. Lu Y, et al. Among authors: gao fb. Mol Brain. 2009 Sep 25;2:30. doi: 10.1186/1756-6606-2-30. Mol Brain. 2009. PMID: 19781077 Free PMC article.

3

FTD/ALS-associated poly(GR) protein impairs the Notch pathway and is recruited by poly(GA) into cytoplasmic inclusions.

Yang D, Abdallah A, Li Z, Lu Y, Almeida S, Gao FB. Yang D, et al. Among authors: gao fb. Acta Neuropathol. 2015 Oct;130(4):525-35. doi: 10.1007/s00401-015-1448-6. Epub 2015 Jun 2. Acta Neuropathol. 2015. PMID: 26031661 Free PMC article.

4

Lost & found: C9ORF72 and the autophagy pathway in ALS/FTD.

Almeida S, Gao FB. Almeida S, et al. Among authors: gao fb. EMBO J. 2016 Jun 15;35(12):1251-3. doi: 10.15252/embj.201694578. Epub 2016 May 6. EMBO J. 2016. PMID: 27154207 Free PMC article.

5

Poly(GR) in C9ORF72-Related ALS/FTD Compromises Mitochondrial Function and Increases Oxidative Stress and DNA Damage in iPSC-Derived Motor Neurons.

Lopez-Gonzalez R, Lu Y, Gendron TF, Karydas A, Tran H, Yang D, Petrucelli L, Miller BL, Almeida S, Gao FB. Lopez-Gonzalez R, et al. Among authors: gao fb. Neuron. 2016 Oct 19;92(2):383-391. doi: 10.1016/j.neuron.2016.09.015. Epub 2016 Oct 6. Neuron. 2016. PMID: 27720481 Free PMC article.

6

Evidence that C9ORF72 Dipeptide Repeat Proteins Associate with U2 snRNP to Cause Mis-splicing in ALS/FTD Patients.

Yin S, Lopez-Gonzalez R, Kunz RC, Gangopadhyay J, Borufka C, Gygi SP, Gao FB, Reed R. Yin S, et al. Among authors: gao fb. Cell Rep. 2017 Jun 13;19(11):2244-2256. doi: 10.1016/j.celrep.2017.05.056. Cell Rep. 2017. PMID: 28614712 Free PMC article.

7

Partial inhibition of the overactivated Ku80-dependent DNA repair pathway rescues neurodegeneration in C9ORF72-ALS/FTD.

Lopez-Gonzalez R, Yang D, Pribadi M, Kim TS, Krishnan G, Choi SY, Lee S, Coppola G, Gao FB. Lopez-Gonzalez R, et al. Among authors: gao fb. Proc Natl Acad Sci U S A. 2019 May 7;116(19):9628-9633. doi: 10.1073/pnas.1901313116. Epub 2019 Apr 24. Proc Natl Acad Sci U S A. 2019. PMID: 31019093 Free PMC article.

8

Production of poly(GA) in C9ORF72 patient motor neurons derived from induced pluripotent stem cells.

Almeida S, Krishnan G, Rushe M, Gu Y, Kankel MW, Gao FB. Almeida S, et al. Among authors: gao fb. Acta Neuropathol. 2019 Dec;138(6):1099-1101. doi: 10.1007/s00401-019-02083-z. Epub 2019 Oct 17. Acta Neuropathol. 2019. PMID: 31624870 Free PMC article. No abstract available.

9

CRISPR deletion of the C9ORF72 promoter in ALS/FTD patient motor neurons abolishes production of dipeptide repeat proteins and rescues neurodegeneration.

Krishnan G, Zhang Y, Gu Y, Kankel MW, Gao FB, Almeida S. Krishnan G, et al. Among authors: gao fb. Acta Neuropathol. 2020 Jul;140(1):81-84. doi: 10.1007/s00401-020-02154-6. Epub 2020 Apr 7. Acta Neuropathol. 2020. PMID: 32266467 Free PMC article. No abstract available.

10

Altered MICOS Morphology and Mitochondrial Ion Homeostasis Contribute to Poly(GR) Toxicity Associated with C9-ALS/FTD.

Li S, Wu Z, Li Y, Tantray I, De Stefani D, Mattarei A, Krishnan G, Gao FB, Vogel H, Lu B. Li S, et al. Among authors: gao fb. Cell Rep. 2020 Aug 4;32(5):107989. doi: 10.1016/j.celrep.2020.107989. Cell Rep. 2020. PMID: 32755582 Free PMC article.

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