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Deletion of NLRX1 increases fatty acid metabolism and prevents diet-induced hepatic steatosis and metabolic syndrome.
Kors L, Rampanelli E, Stokman G, Butter LM, Held NM, Claessen N, Larsen PWB, Verheij J, Zuurbier CJ, Liebisch G, Schmitz G, Girardin SE, Florquin S, Houtkooper RH, Leemans JC. Kors L, et al. Among authors: held nm. Biochim Biophys Acta Mol Basis Dis. 2018 May;1864(5 Pt A):1883-1895. doi: 10.1016/j.bbadis.2018.03.003. Epub 2018 Mar 4. Biochim Biophys Acta Mol Basis Dis. 2018. PMID: 29514047 Free article.
Barth syndrome cells display widespread remodeling of mitochondrial complexes without affecting metabolic flux distribution.
Chatzispyrou IA, Guerrero-Castillo S, Held NM, Ruiter JPN, Denis SW, IJlst L, Wanders RJ, van Weeghel M, Ferdinandusse S, Vaz FM, Brandt U, Houtkooper RH. Chatzispyrou IA, et al. Among authors: held nm. Biochim Biophys Acta Mol Basis Dis. 2018 Nov;1864(11):3650-3658. doi: 10.1016/j.bbadis.2018.08.041. Epub 2018 Sep 1. Biochim Biophys Acta Mol Basis Dis. 2018. PMID: 30251684 Free article.
A single day of high-fat diet feeding induces lipid accumulation and insulin resistance in brown adipose tissue in mice.
Kuipers EN, Held NM, In Het Panhuis W, Modder M, Ruppert PMM, Kersten S, Kooijman S, Guigas B, Houtkooper RH, Rensen PCN, Boon MR. Kuipers EN, et al. Among authors: held nm. Am J Physiol Endocrinol Metab. 2019 Nov 1;317(5):E820-E830. doi: 10.1152/ajpendo.00123.2019. Epub 2019 Aug 6. Am J Physiol Endocrinol Metab. 2019. PMID: 31386566 Free article.
The Antibiotic Doxycycline Impairs Cardiac Mitochondrial and Contractile Function.
Wüst RCI, Coolen BF, Held NM, Daal MRR, Alizadeh Tazehkandi V, Baks-Te Bulte L, Wiersma M, Kuster DWD, Brundel BJJM, van Weeghel M, Strijkers GJ, Houtkooper RH. Wüst RCI, et al. Among authors: held nm. Int J Mol Sci. 2021 Apr 15;22(8):4100. doi: 10.3390/ijms22084100. Int J Mol Sci. 2021. PMID: 33921053 Free PMC article.
11 results