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Islet-reactive CD8+ T cell frequencies in the pancreas, but not in blood, distinguish type 1 diabetic patients from healthy donors.
Culina S, Lalanne AI, Afonso G, Cerosaletti K, Pinto S, Sebastiani G, Kuranda K, Nigi L, Eugster A, Østerbye T, Maugein A, McLaren JE, Ladell K, Larger E, Beressi JP, Lissina A, Appay V, Davidson HW, Buus S, Price DA, Kuhn M, Bonifacio E, Battaglia M, Caillat-Zucman S, Dotta F, Scharfmann R, Kyewski B, Mallone R; ImMaDiab Study Group. Culina S, et al. Among authors: ladell k. Sci Immunol. 2018 Feb 2;3(20):eaao4013. doi: 10.1126/sciimmunol.aao4013. Sci Immunol. 2018. PMID: 29429978 Free PMC article.
Techniques to improve the direct ex vivo detection of low frequency antigen-specific CD8+ T cells with peptide-major histocompatibility complex class I tetramers.
Chattopadhyay PK, Melenhorst JJ, Ladell K, Gostick E, Scheinberg P, Barrett AJ, Wooldridge L, Roederer M, Sewell AK, Price DA. Chattopadhyay PK, et al. Among authors: ladell k. Cytometry A. 2008 Nov;73(11):1001-9. doi: 10.1002/cyto.a.20642. Cytometry A. 2008. PMID: 18836993 Free PMC article. Review.
Protein kinase inhibitors substantially improve the physical detection of T-cells with peptide-MHC tetramers.
Lissina A, Ladell K, Skowera A, Clement M, Edwards E, Seggewiss R, van den Berg HA, Gostick E, Gallagher K, Jones E, Melenhorst JJ, Godkin AJ, Peakman M, Price DA, Sewell AK, Wooldridge L. Lissina A, et al. Among authors: ladell k. J Immunol Methods. 2009 Jan 1;340(1):11-24. doi: 10.1016/j.jim.2008.09.014. Epub 2008 Oct 16. J Immunol Methods. 2009. PMID: 18929568 Free PMC article.
MHC class I molecules with Superenhanced CD8 binding properties bypass the requirement for cognate TCR recognition and nonspecifically activate CTLs.
Wooldridge L, Clement M, Lissina A, Edwards ES, Ladell K, Ekeruche J, Hewitt RE, Laugel B, Gostick E, Cole DK, Debets R, Berrevoets C, Miles JJ, Burrows SR, Price DA, Sewell AK. Wooldridge L, et al. Among authors: ladell k. J Immunol. 2010 Apr 1;184(7):3357-66. doi: 10.4049/jimmunol.0902398. Epub 2010 Feb 26. J Immunol. 2010. PMID: 20190139 Free PMC article.
IL-10 restricts memory T cell inflation during cytomegalovirus infection.
Jones M, Ladell K, Wynn KK, Stacey MA, Quigley MF, Gostick E, Price DA, Humphreys IR. Jones M, et al. Among authors: ladell k. J Immunol. 2010 Sep 15;185(6):3583-92. doi: 10.4049/jimmunol.1001535. Epub 2010 Aug 16. J Immunol. 2010. PMID: 20713884 Free PMC article.
113 results