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PI3K-Akt signaling controls PFKFB3 expression during human T-lymphocyte activation.
Simon-Molas H, Arnedo-Pac C, Fontova P, Vidal-Alabró A, Castaño E, Rodríguez-García A, Navarro-Sabaté À, Lloberas N, Manzano A, Bartrons R. Simon-Molas H, et al. Among authors: castano e. Mol Cell Biochem. 2018 Nov;448(1-2):187-197. doi: 10.1007/s11010-018-3325-9. Epub 2018 Feb 12. Mol Cell Biochem. 2018. PMID: 29435871
The potential utility of PFKFB3 as a therapeutic target.
Bartrons R, Rodríguez-García A, Simon-Molas H, Castaño E, Manzano A, Navarro-Sabaté À. Bartrons R, et al. Among authors: castano e. Expert Opin Ther Targets. 2018 Aug;22(8):659-674. doi: 10.1080/14728222.2018.1498082. Epub 2018 Jul 16. Expert Opin Ther Targets. 2018. PMID: 29985086 Review.
Akt mediates TIGAR induction in HeLa cells following PFKFB3 inhibition.
Simon-Molas H, Calvo-Vidal MN, Castaño E, Rodríguez-García A, Navarro-Sabaté À, Bartrons R, Manzano A. Simon-Molas H, et al. Among authors: castano e. FEBS Lett. 2016 Sep;590(17):2915-26. doi: 10.1002/1873-3468.12338. Epub 2016 Aug 24. FEBS Lett. 2016. PMID: 27491040 Free article.
TGF-β1 targets Smad, p38 MAPK, and PI3K/Akt signaling pathways to induce PFKFB3 gene expression and glycolysis in glioblastoma cells.
Rodríguez-García A, Samsó P, Fontova P, Simon-Molas H, Manzano A, Castaño E, Rosa JL, Martinez-Outshoorn U, Ventura F, Navarro-Sabaté À, Bartrons R. Rodríguez-García A, et al. Among authors: castano e. FEBS J. 2017 Oct;284(20):3437-3454. doi: 10.1111/febs.14201. Epub 2017 Sep 10. FEBS J. 2017. PMID: 28834297 Free article.
Fructose 2,6-Bisphosphate in Cancer Cell Metabolism.
Bartrons R, Simon-Molas H, Rodríguez-García A, Castaño E, Navarro-Sabaté À, Manzano A, Martinez-Outschoorn UE. Bartrons R, et al. Among authors: castano e. Front Oncol. 2018 Sep 4;8:331. doi: 10.3389/fonc.2018.00331. eCollection 2018. Front Oncol. 2018. PMID: 30234009 Free PMC article. Review.
257 results