Tosi D - Search Results

1

Strategies for clinical development of monoclonal antibodies beyond first-in-human trials: tested doses and rationale for dose selection.

Viala M, Vinches M, Alexandre M, Mollevi C, Durigova A, Hayaoui N, Homicsko K, Cuenant A, Gongora C, Gianni L, Tosi D. Viala M, et al. Among authors: tosi d. Br J Cancer. 2018 Mar 6;118(5):679-697. doi: 10.1038/bjc.2017.473. Epub 2018 Feb 13. Br J Cancer. 2018. PMID: 29438365 Free PMC article.

2

Phase I study of bortezomib with weekly paclitaxel in patients with advanced solid tumours.

Cresta S, Sessa C, Catapano CV, Gallerani E, Passalacqua D, Rinaldi A, Bertoni F, Viganò L, Maur M, Capri G, Maccioni E, Tosi D, Gianni L. Cresta S, et al. Among authors: tosi d. Eur J Cancer. 2008 Sep;44(13):1829-34. doi: 10.1016/j.ejca.2008.05.022. Epub 2008 Jul 17. Eur J Cancer. 2008. PMID: 18640031 Clinical Trial.

3

A phase I pharmacokinetic study of the vascular disrupting agent ombrabulin (AVE8062) and docetaxel in advanced solid tumours.

Eskens FA, Tresca P, Tosi D, Van Doorn L, Fontaine H, Van der Gaast A, Veyrat-Follet C, Oprea C, Hospitel M, Dieras V. Eskens FA, et al. Among authors: tosi d. Br J Cancer. 2014 Apr 29;110(9):2170-7. doi: 10.1038/bjc.2014.137. Epub 2014 Apr 8. Br J Cancer. 2014. PMID: 24714750 Free PMC article. Clinical Trial.

4

Clinical Development Strategies and Outcomes in First-in-Human Trials of Monoclonal Antibodies.

Tosi D, Laghzali Y, Vinches M, Alexandre M, Homicsko K, Fasolo A, Del Conte G, Durigova A, Hayaoui N, Gourgou S, Gianni L, Mollevi C. Tosi D, et al. J Clin Oncol. 2015 Jul 1;33(19):2158-65. doi: 10.1200/JCO.2014.58.1082. Epub 2015 May 26. J Clin Oncol. 2015. PMID: 26014300 Review.

5

FOXO3a and the MAPK p38 are activated by cetuximab to induce cell death and inhibit cell proliferation and their expression predicts cetuximab efficacy in colorectal cancer.

Marzi L, Combes E, Vié N, Ayrolles-Torro A, Tosi D, Desigaud D, Perez-Gracia E, Larbouret C, Montagut C, Iglesias M, Jarlier M, Denis V, Linares LK, Lam EW, Martineau P, Del Rio M, Gongora C. Marzi L, et al. Among authors: tosi d. Br J Cancer. 2016 Nov 8;115(10):1223-1233. doi: 10.1038/bjc.2016.313. Epub 2016 Sep 29. Br J Cancer. 2016. PMID: 27685445 Free PMC article.

6

Rational development of synergistic combinations of chemotherapy and molecular targeted agents for colorectal cancer treatment.

Tosi D, Pérez-Gracia E, Atis S, Vié N, Combès E, Gabanou M, Larbouret C, Jarlier M, Mollevi C, Torro A, Del Rio M, Martineau P, Gongora C. Tosi D, et al. BMC Cancer. 2018 Aug 13;18(1):812. doi: 10.1186/s12885-018-4712-z. BMC Cancer. 2018. PMID: 30103709 Free PMC article.

7

Inhibition of Ataxia-Telangiectasia Mutated and RAD3-Related (ATR) Overcomes Oxaliplatin Resistance and Promotes Antitumor Immunity in Colorectal Cancer.

Combès E, Andrade AF, Tosi D, Michaud HA, Coquel F, Garambois V, Desigaud D, Jarlier M, Coquelle A, Pasero P, Bonnefoy N, Moreaux J, Martineau P, Del Rio M, Beijersbergen RL, Vezzio-Vie N, Gongora C. Combès E, et al. Among authors: tosi d. Cancer Res. 2019 Jun 1;79(11):2933-2946. doi: 10.1158/0008-5472.CAN-18-2807. Epub 2019 Apr 15. Cancer Res. 2019. PMID: 30987998

8

[Determining the dose to be injected in the first clinical trials with monoclonal antibodies: not so easy!].

Viala M, Tosi D. Viala M, et al. Among authors: tosi d. Med Sci (Paris). 2019 Dec;35(12):1121-1129. doi: 10.1051/medsci/2019209. Epub 2020 Jan 6. Med Sci (Paris). 2019. PMID: 31903926 Free article. Review. French.

9

GUIP1: a R package for dose escalation strategies in phase I cancer clinical trials.

Dinart D, Fraisse J, Tosi D, Mauguen A, Touraine C, Gourgou S, Le Deley MC, Bellera C, Mollevi C. Dinart D, et al. Among authors: tosi d. BMC Med Inform Decis Mak. 2020 Jun 24;20(1):134. doi: 10.1186/s12911-020-01149-3. BMC Med Inform Decis Mak. 2020. PMID: 32580715 Free PMC article.

10

Optimal biological dose: a systematic review in cancer phase I clinical trials.

Fraisse J, Dinart D, Tosi D, Bellera C, Mollevi C. Fraisse J, et al. Among authors: tosi d. BMC Cancer. 2021 Jan 13;21(1):60. doi: 10.1186/s12885-021-07782-z. BMC Cancer. 2021. PMID: 33441097 Free PMC article.

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