Roux PP - Search Results

1

RSK Regulates PFK-2 Activity to Promote Metabolic Rewiring in Melanoma.

Houles T, Gravel SP, Lavoie G, Shin S, Savall M, Méant A, Grondin B, Gaboury L, Yoon SO, St-Pierre J, Roux PP. Houles T, et al. Among authors: roux pp. Cancer Res. 2018 May 1;78(9):2191-2204. doi: 10.1158/0008-5472.CAN-17-2215. Epub 2018 Feb 12. Cancer Res. 2018. PMID: 29440170

2

The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity.

Shahbazian D, Roux PP, Mieulet V, Cohen MS, Raught B, Taunton J, Hershey JW, Blenis J, Pende M, Sonenberg N. Shahbazian D, et al. Among authors: roux pp. EMBO J. 2006 Jun 21;25(12):2781-91. doi: 10.1038/sj.emboj.7601166. Epub 2006 Jun 8. EMBO J. 2006. PMID: 16763566 Free PMC article.

3

RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation.

Roux PP, Shahbazian D, Vu H, Holz MK, Cohen MS, Taunton J, Sonenberg N, Blenis J. Roux PP, et al. J Biol Chem. 2007 May 11;282(19):14056-64. doi: 10.1074/jbc.M700906200. Epub 2007 Mar 14. J Biol Chem. 2007. PMID: 17360704 Free PMC article.

4

The RSK factors of activating the Ras/MAPK signaling cascade.

Carriere A, Ray H, Blenis J, Roux PP. Carriere A, et al. Among authors: roux pp. Front Biosci. 2008 May 1;13:4258-75. doi: 10.2741/3003. Front Biosci. 2008. PMID: 18508509 Review.

5

Oncogenic MAPK signaling stimulates mTORC1 activity by promoting RSK-mediated raptor phosphorylation.

Carrière A, Cargnello M, Julien LA, Gao H, Bonneil E, Thibault P, Roux PP. Carrière A, et al. Among authors: roux pp. Curr Biol. 2008 Sep 9;18(17):1269-77. doi: 10.1016/j.cub.2008.07.078. Epub 2008 Aug 21. Curr Biol. 2008. PMID: 18722121 Free article.

6

Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation.

Choo AY, Yoon SO, Kim SG, Roux PP, Blenis J. Choo AY, et al. Among authors: roux pp. Proc Natl Acad Sci U S A. 2008 Nov 11;105(45):17414-9. doi: 10.1073/pnas.0809136105. Epub 2008 Oct 27. Proc Natl Acad Sci U S A. 2008. PMID: 18955708 Free PMC article.

7

mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling.

Julien LA, Carriere A, Moreau J, Roux PP. Julien LA, et al. Among authors: roux pp. Mol Cell Biol. 2010 Feb;30(4):908-21. doi: 10.1128/MCB.00601-09. Epub 2009 Dec 7. Mol Cell Biol. 2010. PMID: 19995915 Free PMC article.

8

Paving the way for targeting RSK in cancer.

Romeo Y, Roux PP. Romeo Y, et al. Among authors: roux pp. Expert Opin Ther Targets. 2011 Jan;15(1):5-9. doi: 10.1517/14728222.2010.531014. Epub 2010 Oct 19. Expert Opin Ther Targets. 2011. PMID: 20958120

9

Regulation and function of the RSK family of protein kinases.

Romeo Y, Zhang X, Roux PP. Romeo Y, et al. Among authors: roux pp. Biochem J. 2012 Jan 15;441(2):553-69. doi: 10.1042/BJ20110289. Biochem J. 2012. PMID: 22187936 Review.

10

RSK regulates activated BRAF signalling to mTORC1 and promotes melanoma growth.

Romeo Y, Moreau J, Zindy PJ, Saba-El-Leil M, Lavoie G, Dandachi F, Baptissart M, Borden KLB, Meloche S, Roux PP. Romeo Y, et al. Among authors: roux pp. Oncogene. 2013 Jun 13;32(24):2917-2926. doi: 10.1038/onc.2012.312. Epub 2012 Jul 16. Oncogene. 2013. PMID: 22797077 Free PMC article.

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