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ADAM17 is required for EGF-R-induced intestinal tumors via IL-6 trans-signaling.
Schmidt S, Schumacher N, Schwarz J, Tangermann S, Kenner L, Schlederer M, Sibilia M, Linder M, Altendorf-Hofmann A, Knösel T, Gruber ES, Oberhuber G, Bolik J, Rehman A, Sinha A, Lokau J, Arnold P, Cabron AS, Zunke F, Becker-Pauly C, Preaudet A, Nguyen P, Huynh J, Afshar-Sterle S, Chand AL, Westermann J, Dempsey PJ, Garbers C, Schmidt-Arras D, Rosenstiel P, Putoczki T, Ernst M, Rose-John S. Schmidt S, et al. Among authors: dempsey pj. J Exp Med. 2018 Apr 2;215(4):1205-1225. doi: 10.1084/jem.20171696. Epub 2018 Feb 22. J Exp Med. 2018. PMID: 29472497 Free PMC article.
Mucus Detachment by Host Metalloprotease Meprin β Requires Shedding of Its Inactive Pro-form, which Is Abrogated by the Pathogenic Protease RgpB.
Wichert R, Ermund A, Schmidt S, Schweinlin M, Ksiazek M, Arnold P, Knittler K, Wilkens F, Potempa B, Rabe B, Stirnberg M, Lucius R, Bartsch JW, Nikolaus S, Falk-Paulsen M, Rosenstiel P, Metzger M, Rose-John S, Potempa J, Hansson GC, Dempsey PJ, Becker-Pauly C. Wichert R, et al. Among authors: dempsey pj. Cell Rep. 2017 Nov 21;21(8):2090-2103. doi: 10.1016/j.celrep.2017.10.087. Cell Rep. 2017. PMID: 29166602 Free article.
Role of ADAM10 in intestinal crypt homeostasis and tumorigenesis.
Dempsey PJ. Dempsey PJ. Biochim Biophys Acta Mol Cell Res. 2017 Nov;1864(11 Pt B):2228-2239. doi: 10.1016/j.bbamcr.2017.07.011. Epub 2017 Jul 22. Biochim Biophys Acta Mol Cell Res. 2017. PMID: 28739265 Free PMC article. Review.
ADAM Proteases and Gastrointestinal Function.
Jones JC, Rustagi S, Dempsey PJ. Jones JC, et al. Among authors: dempsey pj. Annu Rev Physiol. 2016;78:243-76. doi: 10.1146/annurev-physiol-021014-071720. Epub 2015 Nov 19. Annu Rev Physiol. 2016. PMID: 26667078 Free PMC article. Review.
Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells.
VanDussen KL, Carulli AJ, Keeley TM, Patel SR, Puthoff BJ, Magness ST, Tran IT, Maillard I, Siebel C, Kolterud Å, Grosse AS, Gumucio DL, Ernst SA, Tsai YH, Dempsey PJ, Samuelson LC. VanDussen KL, et al. Among authors: dempsey pj. Development. 2012 Feb;139(3):488-97. doi: 10.1242/dev.070763. Epub 2011 Dec 21. Development. 2012. PMID: 22190634 Free PMC article.
181 results