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A novel platform for engineering blood-brain barrier-crossing bispecific biologics.
Farrington GK, Caram-Salas N, Haqqani AS, Brunette E, Eldredge J, Pepinsky B, Antognetti G, Baumann E, Ding W, Garber E, Jiang S, Delaney C, Boileau E, Sisk WP, Stanimirovic DB. Farrington GK, et al. Among authors: delaney c. FASEB J. 2014 Nov;28(11):4764-78. doi: 10.1096/fj.14-253369. Epub 2014 Jul 28. FASEB J. 2014. PMID: 25070367
Intracellular sorting and transcytosis of the rat transferrin receptor antibody OX26 across the blood-brain barrier in vitro is dependent on its binding affinity.
Haqqani AS, Thom G, Burrell M, Delaney CE, Brunette E, Baumann E, Sodja C, Jezierski A, Webster C, Stanimirovic DB. Haqqani AS, et al. Among authors: delaney ce. J Neurochem. 2018 Sep;146(6):735-752. doi: 10.1111/jnc.14482. Epub 2018 Aug 16. J Neurochem. 2018. PMID: 29877588 Free PMC article.
Differential expression of receptors mediating receptor-mediated transcytosis (RMT) in brain microvessels, brain parenchyma and peripheral tissues of the mouse and the human.
Zhang W, Liu QY, Haqqani AS, Leclerc S, Liu Z, Fauteux F, Baumann E, Delaney CE, Ly D, Star AT, Brunette E, Sodja C, Hewitt M, Sandhu JK, Stanimirovic DB. Zhang W, et al. Among authors: delaney ce. Fluids Barriers CNS. 2020 Jul 22;17(1):47. doi: 10.1186/s12987-020-00209-0. Fluids Barriers CNS. 2020. PMID: 32698806 Free PMC article.
923 results