Webster CI - Search Results

1

Enhanced Delivery of Galanin Conjugates to the Brain through Bioengineering of the Anti-Transferrin Receptor Antibody OX26.

Thom G, Burrell M, Haqqani AS, Yogi A, Lessard E, Brunette E, Delaney C, Baumann E, Callaghan D, Rodrigo N, Webster CI, Stanimirovic DB. Thom G, et al. Among authors: webster ci. Mol Pharm. 2018 Apr 2;15(4):1420-1431. doi: 10.1021/acs.molpharmaceut.7b00937. Epub 2018 Mar 6. Mol Pharm. 2018. PMID: 29485883

2

A variant human IgG1-Fc mediates improved ADCC.

Stewart R, Thom G, Levens M, Güler-Gane G, Holgate R, Rudd PM, Webster C, Jermutus L, Lund J. Stewart R, et al. Protein Eng Des Sel. 2011 Sep;24(9):671-8. doi: 10.1093/protein/gzr015. Epub 2011 May 18. Protein Eng Des Sel. 2011. PMID: 21596686

3

Monovalent IgG4 molecules: immunoglobulin Fc mutations that result in a monomeric structure.

Wilkinson IC, Fowler SB, Machiesky L, Miller K, Hayes DB, Adib M, Her C, Borrok MJ, Tsui P, Burrell M, Corkill DJ, Witt S, Lowe DC, Webster CI. Wilkinson IC, et al. Among authors: webster ci. MAbs. 2013 May-Jun;5(3):406-17. doi: 10.4161/mabs.23941. Epub 2013 Apr 8. MAbs. 2013. PMID: 23567207 Free PMC article.

4

Modelling the endothelial blood-CNS barriers: a method for the production of robust in vitro models of the rat blood-brain barrier and blood-spinal cord barrier.

Watson PM, Paterson JC, Thom G, Ginman U, Lundquist S, Webster CI. Watson PM, et al. Among authors: webster ci. BMC Neurosci. 2013 Jun 18;14:59. doi: 10.1186/1471-2202-14-59. BMC Neurosci. 2013. PMID: 23773766 Free PMC article.

5

Sustained peripheral depletion of amyloid-β with a novel form of neprilysin does not affect central levels of amyloid-β.

Henderson SJ, Andersson C, Narwal R, Janson J, Goldschmidt TJ, Appelkvist P, Bogstedt A, Steffen AC, Haupts U, Tebbe J, Freskgård PO, Jermutus L, Burrell M, Fowler SB, Webster CI. Henderson SJ, et al. Among authors: webster ci. Brain. 2014 Feb;137(Pt 2):553-64. doi: 10.1093/brain/awt308. Epub 2013 Nov 20. Brain. 2014. PMID: 24259408 Free PMC article.

6

Engineering neprilysin activity and specificity to create a novel therapeutic for Alzheimer's disease.

Webster CI, Burrell M, Olsson LL, Fowler SB, Digby S, Sandercock A, Snijder A, Tebbe J, Haupts U, Grudzinska J, Jermutus L, Andersson C. Webster CI, et al. PLoS One. 2014 Aug 4;9(8):e104001. doi: 10.1371/journal.pone.0104001. eCollection 2014. PLoS One. 2014. PMID: 25089527 Free PMC article.

7

A gateway to the brain: shuttles for brain delivery of macromolecules.

Webster CI, Stanimirovic DB. Webster CI, et al. Ther Deliv. 2015;6(12):1321-4. doi: 10.4155/tde.15.78. Ther Deliv. 2015. PMID: 26652278 No abstract available.

8

Brain penetration, target engagement, and disposition of the blood-brain barrier-crossing bispecific antibody antagonist of metabotropic glutamate receptor type 1.

Webster CI, Caram-Salas N, Haqqani AS, Thom G, Brown L, Rennie K, Yogi A, Costain W, Brunette E, Stanimirovic DB. Webster CI, et al. FASEB J. 2016 May;30(5):1927-40. doi: 10.1096/fj.201500078. Epub 2016 Feb 2. FASEB J. 2016. PMID: 26839377

9

Neprilysin Inhibits Coagulation through Proteolytic Inactivation of Fibrinogen.

Burrell M, Henderson SJ, Ravnefjord A, Schweikart F, Fowler SB, Witt S, Hansson KM, Webster CI. Burrell M, et al. Among authors: webster ci. PLoS One. 2016 Jul 20;11(7):e0158114. doi: 10.1371/journal.pone.0158114. eCollection 2016. PLoS One. 2016. PMID: 27437944 Free PMC article.

10

Exploiting transferrin receptor for delivering drugs across the blood-brain barrier.

Paterson J, Webster CI. Paterson J, et al. Among authors: webster ci. Drug Discov Today Technol. 2016 Jun;20:49-52. doi: 10.1016/j.ddtec.2016.07.009. Epub 2016 Oct 27. Drug Discov Today Technol. 2016. PMID: 27986223 Free article. Review.

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