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Live Respiratory Syncytial Virus (RSV) Vaccine Candidate Containing Stabilized Temperature-Sensitivity Mutations Is Highly Attenuated in RSV-Seronegative Infants and Children.
Buchholz UJ, Cunningham CK, Muresan P, Gnanashanmugam D, Sato P, Siberry GK, Rexroad V, Valentine M, Perlowski C, Schappell E, Thumar B, Luongo C, Barr E, Aziz M, Yogev R, Spector SA, Collins PL, McFarland EJ, Karron RA; International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) P1114 Study Team. Buchholz UJ, et al. Among authors: collins pl. J Infect Dis. 2018 Apr 11;217(9):1338-1346. doi: 10.1093/infdis/jiy066. J Infect Dis. 2018. PMID: 29509929 Free PMC article. Clinical Trial.
Resistance to respiratory syncytial virus (RSV) challenge induced by infection with a vaccinia virus recombinant expressing the RSV M2 protein (Vac-M2) is mediated by CD8+ T cells, while that induced by Vac-F or Vac-G recombinants is mediated by antibodies.
Connors M, Kulkarni AB, Collins PL, Firestone CY, Holmes KL, Morse HC 3rd, Murphy BR. Connors M, et al. Among authors: collins pl. J Virol. 1992 Feb;66(2):1277-81. doi: 10.1128/JVI.66.2.1277-1281.1992. J Virol. 1992. PMID: 1731105 Free PMC article.
Live viral vaccines for respiratory and enteric tract diseases.
Chanock RM, Murphy BR, Collins PL, Coelingh KV, Olmsted RA, Snyder MH, Spriggs MK, Prince GA, Moss B, Flores J, et al. Chanock RM, et al. Among authors: collins pl. Vaccine. 1988 Apr;6(2):129-33. doi: 10.1016/s0264-410x(88)80014-8. Vaccine. 1988. PMID: 2838984 Review.
446 results