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Interleukin-7 restores lymphocytes in septic shock: the IRIS-7 randomized clinical trial.
Francois B, Jeannet R, Daix T, Walton AH, Shotwell MS, Unsinger J, Monneret G, Rimmelé T, Blood T, Morre M, Gregoire A, Mayo GA, Blood J, Durum SK, Sherwood ER, Hotchkiss RS. Francois B, et al. Among authors: blood t, blood j. JCI Insight. 2018 Mar 8;3(5):e98960. doi: 10.1172/jci.insight.98960. JCI Insight. 2018. PMID: 29515037 Free PMC article. Clinical Trial.
Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections.
Remy KE, Mazer M, Striker DA, Ellebedy AH, Walton AH, Unsinger J, Blood TM, Mudd PA, Yi DJ, Mannion DA, Osborne DF, Martin RS, Anand NJ, Bosanquet JP, Blood J, Drewry AM, Caldwell CC, Turnbull IR, Brakenridge SC, Moldwawer LL, Hotchkiss RS. Remy KE, et al. JCI Insight. 2020 Sep 3;5(17):e140329. doi: 10.1172/jci.insight.140329. JCI Insight. 2020. PMID: 32687484 Free PMC article.
ELISpot, a highly sensitive, functional immunoassay, was employed in 27 patients with COVID-19, 51 patients with sepsis, 18 critically ill nonseptic (CINS) patients, and 27 healthy control volunteers to evaluate adaptive and innate immune status by quantitating T cell IFN- …
ELISpot, a highly sensitive, functional immunoassay, was employed in 27 patients with COVID-19, 51 patients with sepsis, 18 critically ill n …
Interleukin-7 Reverses Lymphopenia and Improves T-Cell Function in Coronavirus Disease 2019 Patient With Inborn Error of Toll-Like Receptor 3: A Case Report.
Mazer MB, Turnbull IR, Miles S, Blood TM, Sadler B, Hess A, Botney MD, Martin RS, Bosanquet JP, Striker DA, Anand NS, Morre M, Caldwell CC, Brakenridge SC, Moldawer LL, Di Paola JA, Hotchkiss RS, Remy KE. Mazer MB, et al. Among authors: blood tm. Crit Care Explor. 2021 Jul 14;3(7):e0500. doi: 10.1097/CCE.0000000000000500. eCollection 2021 Jul. Crit Care Explor. 2021. PMID: 34345826 Free PMC article.
Intravenously administered interleukin-7 to reverse lymphopenia in patients with septic shock: a double-blind, randomized, placebo-controlled trial.
Daix T, Mathonnet A, Brakenridge S, Dequin PF, Mira JP, Berbille F, Morre M, Jeannet R, Blood T, Unsinger J, Blood J, Walton A, Moldawer LL, Hotchkiss R, François B. Daix T, et al. Among authors: blood t. Ann Intensive Care. 2023 Mar 12;13(1):17. doi: 10.1186/s13613-023-01109-w. Ann Intensive Care. 2023. PMID: 36906875 Free PMC article.
Severe Acute Respiratory Syndrome-Associated Coronavirus 2 Infection and Organ Dysfunction in the ICU: Opportunities for Translational Research.
Verhoef PA, Kannan S, Sturgill JL, Tucker EW, Morris PE, Miller AC, Sexton TR, Koyner JL, Hejal R, Brakenridge SC, Moldawer LL, Hotchkiss RS, Blood TM, Mazer MB, Bolesta S, Alexander SA, Armaignac DL, Shein SL, Jones C, Hoemann CD, Doctor A, Friess SH, Parker RI, Rotta AT, Remy KE. Verhoef PA, et al. Among authors: blood tm. Crit Care Explor. 2021 Mar 12;3(3):e0374. doi: 10.1097/CCE.0000000000000374. eCollection 2021 Mar. Crit Care Explor. 2021. PMID: 33786450 Free PMC article. Review.
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