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Page 1
Structure-Activity Investigation of a G Protein-Biased Agonist Reveals Molecular Determinants for Biased Signaling of the D2 Dopamine Receptor.
Chun LS, Vekariya RH, Free RB, Li Y, Lin DT, Su P, Liu F, Namkung Y, Laporte SA, Moritz AE, Aubé J, Frankowski KJ, Sibley DR. Chun LS, et al. Among authors: vekariya rh. Front Synaptic Neurosci. 2018 Feb 21;10:2. doi: 10.3389/fnsyn.2018.00002. eCollection 2018. Front Synaptic Neurosci. 2018. PMID: 29515433 Free PMC article.
Reformulating a Pharmacophore for 5-HT2A Serotonin Receptor Antagonists.
Younkin J, Gaitonde SA, Ellaithy A, Vekariya R, Baki L, Moreno JL, Shah S, Drossopoulos P, Hideshima KS, Eltit JM, González-Maeso J, Logothetis DE, Dukat M, Glennon RA. Younkin J, et al. ACS Chem Neurosci. 2016 Sep 21;7(9):1292-9. doi: 10.1021/acschemneuro.6b00162. Epub 2016 Jul 19. ACS Chem Neurosci. 2016. PMID: 27385190 Free PMC article.
Synthesis and Structure-Activity Relationships of 5'-Aryl-14-alkoxypyridomorphinans: Identification of a μ Opioid Receptor Agonist/δ Opioid Receptor Antagonist Ligand with Systemic Antinociceptive Activity and Diminished Opioid Side Effects.
Vekariya RH, Lei W, Ray A, Saini SK, Zhang S, Molnar G, Barlow D, Karlage KL, Bilsky EJ, Houseknecht KL, Largent-Milnes TM, Streicher JM, Ananthan S. Vekariya RH, et al. J Med Chem. 2020 Jul 23;63(14):7663-7694. doi: 10.1021/acs.jmedchem.0c00503. Epub 2020 Jun 30. J Med Chem. 2020. PMID: 32530286 Free PMC article.
SRI-32743, a novel allosteric modulator, attenuates HIV-1 Tat protein-induced inhibition of the dopamine transporter and alleviates the potentiation of cocaine reward in HIV-1 Tat transgenic mice.
Zhu J, Quizon PM, Wang Y, Adeniran CA, Strauss MJ, Jiménez-Torres AC, Patel P, Cirino TJ, Eans SO, Hammond HR, Deliscar LS, O'Hara P, Saini SK, Ofori E, Vekariya RH, Zhang S, Moukha-Chafiq O, Nguyen TH, Ananthan S, Augelli-Szafran CE, Zhan CG, McLaughlin JP. Zhu J, et al. Among authors: vekariya rh. Neuropharmacology. 2022 Dec 1;220:109239. doi: 10.1016/j.neuropharm.2022.109239. Epub 2022 Sep 17. Neuropharmacology. 2022. PMID: 36126727
12 results