Vakoc CR - Search Results

1

LKB1, Salt-Inducible Kinases, and MEF2C Are Linked Dependencies in Acute Myeloid Leukemia.

Tarumoto Y, Lu B, Somerville TDD, Huang YH, Milazzo JP, Wu XS, Klingbeil O, El Demerdash O, Shi J, Vakoc CR. Tarumoto Y, et al. Among authors: vakoc cr. Mol Cell. 2018 Mar 15;69(6):1017-1027.e6. doi: 10.1016/j.molcel.2018.02.011. Epub 2018 Mar 8. Mol Cell. 2018. PMID: 29526696 Free PMC article.

2

Proximity among distant regulatory elements at the beta-globin locus requires GATA-1 and FOG-1.

Vakoc CR, Letting DL, Gheldof N, Sawado T, Bender MA, Groudine M, Weiss MJ, Dekker J, Blobel GA. Vakoc CR, et al. Mol Cell. 2005 Feb 4;17(3):453-62. doi: 10.1016/j.molcel.2004.12.028. Mol Cell. 2005. PMID: 15694345 Free article.

3

Exchange of GATA factors mediates transitions in looped chromatin organization at a developmentally regulated gene locus.

Jing H, Vakoc CR, Ying L, Mandat S, Wang H, Zheng X, Blobel GA. Jing H, et al. Among authors: vakoc cr. Mol Cell. 2008 Feb 1;29(2):232-42. doi: 10.1016/j.molcel.2007.11.020. Mol Cell. 2008. PMID: 18243117 Free PMC article.

4

A reconfigured pattern of MLL occupancy within mitotic chromatin promotes rapid transcriptional reactivation following mitotic exit.

Blobel GA, Kadauke S, Wang E, Lau AW, Zuber J, Chou MM, Vakoc CR. Blobel GA, et al. Among authors: vakoc cr. Mol Cell. 2009 Dec 25;36(6):970-83. doi: 10.1016/j.molcel.2009.12.001. Mol Cell. 2009. PMID: 20064463 Free PMC article.

5

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia.

Zuber J, Shi J, Wang E, Rappaport AR, Herrmann H, Sison EA, Magoon D, Qi J, Blatt K, Wunderlich M, Taylor MJ, Johns C, Chicas A, Mulloy JC, Kogan SC, Brown P, Valent P, Bradner JE, Lowe SW, Vakoc CR. Zuber J, et al. Among authors: vakoc cr. Nature. 2011 Aug 3;478(7370):524-8. doi: 10.1038/nature10334. Nature. 2011. PMID: 21814200 Free PMC article.

6

An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance.

Zuber J, Rappaport AR, Luo W, Wang E, Chen C, Vaseva AV, Shi J, Weissmueller S, Fellmann C, Taylor MJ, Weissenboeck M, Graeber TG, Kogan SC, Vakoc CR, Lowe SW. Zuber J, et al. Among authors: vakoc cr. Genes Dev. 2011 Aug 1;25(15):1628-40. doi: 10.1101/gad.17269211. Genes Dev. 2011. PMID: 21828272 Free PMC article.

7

The Polycomb complex PRC2 supports aberrant self-renewal in a mouse model of MLL-AF9;Nras(G12D) acute myeloid leukemia.

Shi J, Wang E, Zuber J, Rappaport A, Taylor M, Johns C, Lowe SW, Vakoc CR. Shi J, et al. Among authors: vakoc cr. Oncogene. 2013 Feb 14;32(7):930-8. doi: 10.1038/onc.2012.110. Epub 2012 Apr 2. Oncogene. 2013. PMID: 22469984 Free PMC article.

8

Small-molecule inhibition of BRD4 as a new potent approach to eliminate leukemic stem- and progenitor cells in acute myeloid leukemia AML.

Herrmann H, Blatt K, Shi J, Gleixner KV, Cerny-Reiterer S, Müllauer L, Vakoc CR, Sperr WR, Horny HP, Bradner JE, Zuber J, Valent P. Herrmann H, et al. Among authors: vakoc cr. Oncotarget. 2012 Dec;3(12):1588-99. doi: 10.18632/oncotarget.733. Oncotarget. 2012. PMID: 23249862 Free PMC article.

9

Histone H2B ubiquitin ligase RNF20 is required for MLL-rearranged leukemia.

Wang E, Kawaoka S, Yu M, Shi J, Ni T, Yang W, Zhu J, Roeder RG, Vakoc CR. Wang E, et al. Among authors: vakoc cr. Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):3901-6. doi: 10.1073/pnas.1301045110. Epub 2013 Feb 14. Proc Natl Acad Sci U S A. 2013. PMID: 23412334 Free PMC article.

10

The ubiquitin ligase FBXW7 modulates leukemia-initiating cell activity by regulating MYC stability.

King B, Trimarchi T, Reavie L, Xu L, Mullenders J, Ntziachristos P, Aranda-Orgilles B, Perez-Garcia A, Shi J, Vakoc C, Sandy P, Shen SS, Ferrando A, Aifantis I. King B, et al. Cell. 2013 Jun 20;153(7):1552-66. doi: 10.1016/j.cell.2013.05.041. Cell. 2013. PMID: 23791182 Free PMC article.

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