Castro A - Search Results

1

Identification of a novel 2-oxindole fluorinated derivative as in vivo antitumor agent for prostate cancer acting via AMPK activation.

Bort A, Quesada S, Ramos-Torres Á, Gargantilla M, Priego EM, Raynal S, Lepifre F, Gasalla JM, Rodriguez-Henche N, Castro A, Díaz-Laviada I. Bort A, et al. Among authors: castro a. Sci Rep. 2018 Mar 12;8(1):4370. doi: 10.1038/s41598-018-22690-2. Sci Rep. 2018. PMID: 29531259 Free PMC article.

2

Novel indolic AMPK modulators induce vasodilatation through activation of the AMPK-eNOS-NO pathway.

Sanz-Gómez M, Aledavood E, Beroiz-Salaverri M, Lagartera L, Vega-Martín E, Gil-Ortega M, Cumella J, Pérez C, Luque FJ, Estarellas C, Fernández-Alfonso MS, Castro A. Sanz-Gómez M, et al. Among authors: castro a. Sci Rep. 2022 Mar 10;12(1):4225. doi: 10.1038/s41598-022-07077-8. Sci Rep. 2022. PMID: 35273216 Free PMC article.

3

Neuroprotective Effect of IND1316, an Indole-Based AMPK Activator, in Animal Models of Huntington Disease.

Vela M, García-Gimeno MA, Sanchis A, Bono-Yagüe J, Cumella J, Lagartera L, Pérez C, Priego EM, Campos A, Sanz P, Vázquez-Manrique RP, Castro A. Vela M, et al. Among authors: castro a. ACS Chem Neurosci. 2022 Jan 19;13(2):275-287. doi: 10.1021/acschemneuro.1c00758. Epub 2021 Dec 28. ACS Chem Neurosci. 2022. PMID: 34962383 Free PMC article.

4

5-imino-1,2,4-thiadiazoles: first small molecules as substrate competitive inhibitors of glycogen synthase kinase 3.

Palomo V, Perez DI, Perez C, Morales-Garcia JA, Soteras I, Alonso-Gil S, Encinas A, Castro A, Campillo NE, Perez-Castillo A, Gil C, Martinez A. Palomo V, et al. Among authors: castro a. J Med Chem. 2012 Feb 23;55(4):1645-61. doi: 10.1021/jm201463v. Epub 2012 Feb 3. J Med Chem. 2012. PMID: 22257026

5

Glycogen synthase kinase 3 (GSK-3) inhibitors as new promising drugs for diabetes, neurodegeneration, cancer, and inflammation.

Martinez A, Castro A, Dorronsoro I, Alonso M. Martinez A, et al. Among authors: castro a. Med Res Rev. 2002 Jul;22(4):373-84. doi: 10.1002/med.10011. Med Res Rev. 2002. PMID: 12111750 Review.

6

Synthesis and potential muscarinic receptor binding and antioxidant properties of 3-(thiadiazolyl)pyridine 1-oxide compounds.

Martinez A, Alonso D, Castro A, Arán VJ, Cardelús I, Baños JE, Badia A. Martinez A, et al. Among authors: castro a. Arch Pharm (Weinheim). 1999 Jun;332(6):191-4. doi: 10.1002/(sici)1521-4184(19996)332:6<191::aid-ardp191>3.0.co;2-x. Arch Pharm (Weinheim). 1999. PMID: 10399487

7

Benzyl derivatives of 2,1,3-benzo- and benzothieno[3,2-a]thiadiazine 2,2-dioxides: first phosphodiesterase 7 inhibitors.

Martínez A, Castro A, Gil C, Miralpeix M, Segarra V, Doménech T, Beleta J, Palacios JM, Ryder H, Miró X, Bonet C, Casacuberta JM, Azorín F, Piña B, Puigdoménech P. Martínez A, et al. Among authors: castro a. J Med Chem. 2000 Feb 24;43(4):683-9. doi: 10.1021/jm990382n. J Med Chem. 2000. PMID: 10691694

8

Chlorophenylmethyl benzothiadiazine dioxides derivatives: potent human cytomegalovirus inhibitors.

Martinez A, Gil C, Perez C, Castro A, Prieto C, Otero J. Martinez A, et al. Among authors: castro a. Bioorg Med Chem Lett. 1999 Nov 1;9(21):3133-6. doi: 10.1016/s0960-894x(99)00538-7. Bioorg Med Chem Lett. 1999. PMID: 10560739

9

Benzothiadiazine dioxide human cytomegalovirus inhibitors: synthesis and antiviral evaluation of main heterocycle modified derivatives.

Martinez A, Gil C, Castro A, Bruno AM, Pérez C, Prieto C, Otero J. Martinez A, et al. Among authors: castro a. Antivir Chem Chemother. 2003 Mar;14(2):107-14. doi: 10.1177/095632020301400206. Antivir Chem Chemother. 2003. PMID: 12856922 Free article.

10

Design and synthesis of N-benzylpiperidine-purine derivatives as new dual inhibitors of acetyl- and butyrylcholinesterase.

Rodríguez-Franco MI, Fernández-Bachiller MI, Pérez C, Castro A, Martínez A. Rodríguez-Franco MI, et al. Among authors: castro a. Bioorg Med Chem. 2005 Dec 15;13(24):6795-802. doi: 10.1016/j.bmc.2005.07.019. Epub 2005 Sep 23. Bioorg Med Chem. 2005. PMID: 16183292

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