Gestaut DR - Search Results

1

The TRiC chaperonin controls reovirus replication through outer-capsid folding.

Knowlton JJ, Fernández de Castro I, Ashbrook AW, Gestaut DR, Zamora PF, Bauer JA, Forrest JC, Frydman J, Risco C, Dermody TS. Knowlton JJ, et al. Among authors: gestaut dr. Nat Microbiol. 2018 Apr;3(4):481-493. doi: 10.1038/s41564-018-0122-x. Epub 2018 Mar 12. Nat Microbiol. 2018. PMID: 29531365 Free PMC article.

2

Structural and functional dissection of reovirus capsid folding and assembly by the prefoldin-TRiC/CCT chaperone network.

Knowlton JJ, Gestaut D, Ma B, Taylor G, Seven AB, Leitner A, Wilson GJ, Shanker S, Yates NA, Prasad BVV, Aebersold R, Chiu W, Frydman J, Dermody TS. Knowlton JJ, et al. Proc Natl Acad Sci U S A. 2021 Mar 16;118(11):e2018127118. doi: 10.1073/pnas.2018127118. Proc Natl Acad Sci U S A. 2021. PMID: 33836586 Free PMC article.

3

The ATP-powered gymnastics of TRiC/CCT: an asymmetric protein folding machine with a symmetric origin story.

Gestaut D, Limatola A, Joachimiak L, Frydman J. Gestaut D, et al. Curr Opin Struct Biol. 2019 Apr;55:50-58. doi: 10.1016/j.sbi.2019.03.002. Epub 2019 Apr 9. Curr Opin Struct Biol. 2019. PMID: 30978594 Free PMC article. Review.

4

The Chaperonin TRiC/CCT Associates with Prefoldin through a Conserved Electrostatic Interface Essential for Cellular Proteostasis.

Gestaut D, Roh SH, Ma B, Pintilie G, Joachimiak LA, Leitner A, Walzthoeni T, Aebersold R, Chiu W, Frydman J. Gestaut D, et al. Cell. 2019 Apr 18;177(3):751-765.e15. doi: 10.1016/j.cell.2019.03.012. Epub 2019 Apr 4. Cell. 2019. PMID: 30955883 Free PMC article.

5

The Ndc80 kinetochore complex directly modulates microtubule dynamics.

Umbreit NT, Gestaut DR, Tien JF, Vollmar BS, Gonen T, Asbury CL, Davis TN. Umbreit NT, et al. Among authors: gestaut dr. Proc Natl Acad Sci U S A. 2012 Oct 2;109(40):16113-8. doi: 10.1073/pnas.1209615109. Epub 2012 Aug 20. Proc Natl Acad Sci U S A. 2012. PMID: 22908300 Free PMC article.

6

Regulation of outer kinetochore Ndc80 complex-based microtubule attachments by the central kinetochore Mis12/MIND complex.

Kudalkar EM, Scarborough EA, Umbreit NT, Zelter A, Gestaut DR, Riffle M, Johnson RS, MacCoss MJ, Asbury CL, Davis TN. Kudalkar EM, et al. Among authors: gestaut dr. Proc Natl Acad Sci U S A. 2015 Oct 13;112(41):E5583-9. doi: 10.1073/pnas.1513882112. Epub 2015 Oct 1. Proc Natl Acad Sci U S A. 2015. PMID: 26430240 Free PMC article.

7

The Dam1 kinetochore complex harnesses microtubule dynamics to produce force and movement.

Asbury CL, Gestaut DR, Powers AF, Franck AD, Davis TN. Asbury CL, et al. Among authors: gestaut dr. Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):9873-8. doi: 10.1073/pnas.0602249103. Epub 2006 Jun 15. Proc Natl Acad Sci U S A. 2006. PMID: 16777964 Free PMC article.

8

Phosphoregulation and depolymerization-driven movement of the Dam1 complex do not require ring formation.

Gestaut DR, Graczyk B, Cooper J, Widlund PO, Zelter A, Wordeman L, Asbury CL, Davis TN. Gestaut DR, et al. Nat Cell Biol. 2008 Apr;10(4):407-14. doi: 10.1038/ncb1702. Epub 2008 Mar 23. Nat Cell Biol. 2008. PMID: 18364702 Free PMC article.

9

Tension applied through the Dam1 complex promotes microtubule elongation providing a direct mechanism for length control in mitosis.

Franck AD, Powers AF, Gestaut DR, Gonen T, Davis TN, Asbury CL. Franck AD, et al. Among authors: gestaut dr. Nat Cell Biol. 2007 Jul;9(7):832-7. doi: 10.1038/ncb1609. Epub 2007 Jun 17. Nat Cell Biol. 2007. PMID: 17572669 Free PMC article.

10

The Ndc80 kinetochore complex forms load-bearing attachments to dynamic microtubule tips via biased diffusion.

Powers AF, Franck AD, Gestaut DR, Cooper J, Gracyzk B, Wei RR, Wordeman L, Davis TN, Asbury CL. Powers AF, et al. Among authors: gestaut dr. Cell. 2009 Mar 6;136(5):865-75. doi: 10.1016/j.cell.2008.12.045. Cell. 2009. PMID: 19269365 Free PMC article.

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