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Functional characterization of the PCLO p.Ser4814Ala variant associated with major depressive disorder reveals cellular but not behavioral differences.
Giniatullina A, Maroteaux G, Geerts CJ, Koopmans B, Loos M, Klaassen R, Chen N, van der Schors RC, van Nierop P, Li KW, de Jong J, Altrock WD, Cornelisse LN, Toonen RF, van der Sluis S, Sullivan PF, Stiedl O, Posthuma D, Smit AB, Groffen AJ, Verhage M. Giniatullina A, et al. Among authors: stiedl o. Neuroscience. 2015 Aug 6;300:518-38. doi: 10.1016/j.neuroscience.2015.05.047. Epub 2015 Jun 1. Neuroscience. 2015. PMID: 26045179
Presynaptic inhibition upon CB1 or mGlu2/3 receptor activation requires ERK/MAPK phosphorylation of Munc18-1.
Schmitz SK, King C, Kortleven C, Huson V, Kroon T, Kevenaar JT, Schut D, Saarloos I, Hoetjes JP, de Wit H, Stiedl O, Spijker S, Li KW, Mansvelder HD, Smit AB, Cornelisse LN, Verhage M, Toonen RF. Schmitz SK, et al. Among authors: stiedl o. EMBO J. 2016 Jun 1;35(11):1236-50. doi: 10.15252/embj.201592244. Epub 2016 Apr 7. EMBO J. 2016. PMID: 27056679 Free PMC article.
High-throughput phenotyping of avoidance learning in mice discriminates different genotypes and identifies a novel gene.
Maroteaux G, Loos M, van der Sluis S, Koopmans B, Aarts E, van Gassen K, Geurts A; NeuroBSIK Mouse Phenomics Consortium; Largaespada DA, Spruijt BM, Stiedl O, Smit AB, Verhage M. Maroteaux G, et al. Among authors: stiedl o. Genes Brain Behav. 2012 Oct;11(7):772-84. doi: 10.1111/j.1601-183X.2012.00820.x. Epub 2012 Aug 2. Genes Brain Behav. 2012. PMID: 22846151 Free PMC article.
67 results