Gan L - Search Results

1

SIRT1 Deacetylates Tau and Reduces Pathogenic Tau Spread in a Mouse Model of Tauopathy.

Min SW, Sohn PD, Li Y, Devidze N, Johnson JR, Krogan NJ, Masliah E, Mok SA, Gestwicki JE, Gan L. Min SW, et al. Among authors: gan l. J Neurosci. 2018 Apr 11;38(15):3680-3688. doi: 10.1523/JNEUROSCI.2369-17.2018. Epub 2018 Mar 14. J Neurosci. 2018. PMID: 29540553 Free PMC article.

2

Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease.

Sanchez-Mejia RO, Newman JW, Toh S, Yu GQ, Zhou Y, Halabisky B, Cissé M, Scearce-Levie K, Cheng IH, Gan L, Palop JJ, Bonventre JV, Mucke L. Sanchez-Mejia RO, et al. Among authors: gan l. Nat Neurosci. 2008 Nov;11(11):1311-8. doi: 10.1038/nn.2213. Epub 2008 Oct 19. Nat Neurosci. 2008. PMID: 18931664 Free PMC article.

3

Cystatin C-cathepsin B axis regulates amyloid beta levels and associated neuronal deficits in an animal model of Alzheimer's disease.

Sun B, Zhou Y, Halabisky B, Lo I, Cho SH, Mueller-Steiner S, Devidze N, Wang X, Grubb A, Gan L. Sun B, et al. Among authors: gan l. Neuron. 2008 Oct 23;60(2):247-57. doi: 10.1016/j.neuron.2008.10.001. Neuron. 2008. PMID: 18957217 Free PMC article.

4

Acetylation of tau inhibits its degradation and contributes to tauopathy.

Min SW, Cho SH, Zhou Y, Schroeder S, Haroutunian V, Seeley WW, Huang EJ, Shen Y, Masliah E, Mukherjee C, Meyers D, Cole PA, Ott M, Gan L. Min SW, et al. Among authors: gan l. Neuron. 2010 Sep 23;67(6):953-66. doi: 10.1016/j.neuron.2010.08.044. Neuron. 2010. PMID: 20869593 Free PMC article.

5

Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury.

Martens LH, Zhang J, Barmada SJ, Zhou P, Kamiya S, Sun B, Min SW, Gan L, Finkbeiner S, Huang EJ, Farese RV Jr. Martens LH, et al. Among authors: gan l. J Clin Invest. 2012 Nov;122(11):3955-9. doi: 10.1172/JCI63113. Epub 2012 Oct 8. J Clin Invest. 2012. PMID: 23041626 Free PMC article.

6

Argyrophilic grain disease differs from other tauopathies by lacking tau acetylation.

Grinberg LT, Wang X, Wang C, Sohn PD, Theofilas P, Sidhu M, Arevalo JB, Heinsen H, Huang EJ, Rosen H, Miller BL, Gan L, Seeley WW. Grinberg LT, et al. Among authors: gan l. Acta Neuropathol. 2013 Apr;125(4):581-93. doi: 10.1007/s00401-013-1080-2. Epub 2013 Jan 31. Acta Neuropathol. 2013. PMID: 23371364 Free PMC article.

7

Sirtuins in neurodegenerative diseases: an update on potential mechanisms.

Min SW, Sohn PD, Cho SH, Swanson RA, Gan L. Min SW, et al. Among authors: gan l. Front Aging Neurosci. 2013 Sep 25;5:53. doi: 10.3389/fnagi.2013.00053. Front Aging Neurosci. 2013. PMID: 24093018 Free PMC article. Review.

8

Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models.

Minami SS, Min SW, Krabbe G, Wang C, Zhou Y, Asgarov R, Li Y, Martens LH, Elia LP, Ward ME, Mucke L, Farese RV Jr, Gan L. Minami SS, et al. Among authors: gan l. Nat Med. 2014 Oct;20(10):1157-64. doi: 10.1038/nm.3672. Epub 2014 Sep 28. Nat Med. 2014. PMID: 25261995 Free PMC article.

9

SIRT1 deficiency in microglia contributes to cognitive decline in aging and neurodegeneration via epigenetic regulation of IL-1β.

Cho SH, Chen JA, Sayed F, Ward ME, Gao F, Nguyen TA, Krabbe G, Sohn PD, Lo I, Minami S, Devidze N, Zhou Y, Coppola G, Gan L. Cho SH, et al. Among authors: gan l. J Neurosci. 2015 Jan 14;35(2):807-18. doi: 10.1523/JNEUROSCI.2939-14.2015. J Neurosci. 2015. PMID: 25589773 Free PMC article.

10

Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.

Min SW, Chen X, Tracy TE, Li Y, Zhou Y, Wang C, Shirakawa K, Minami SS, Defensor E, Mok SA, Sohn PD, Schilling B, Cong X, Ellerby L, Gibson BW, Johnson J, Krogan N, Shamloo M, Gestwicki J, Masliah E, Verdin E, Gan L. Min SW, et al. Among authors: gan l. Nat Med. 2015 Oct;21(10):1154-62. doi: 10.1038/nm.3951. Epub 2015 Sep 21. Nat Med. 2015. PMID: 26390242 Free PMC article.

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