Graham SL - Search Results

1

Identification of second-generation P2X3 antagonists for treatment of pain.

Ginnetti AT, Paone DV, Stauffer SR, Potteiger CM, Shaw AW, Deng J, Mulhearn JJ, Nguyen DN, Segerdell C, Anquandah J, Calamari A, Cheng G, Leitl MD, Liang A, Moore E, Panigel J, Urban M, Wang J, Fillgrove K, Tang C, Cook S, Kane S, Salvatore CA, Graham SL, Burgey CS. Ginnetti AT, et al. Among authors: graham sl. Bioorg Med Chem Lett. 2018 May 1;28(8):1392-1396. doi: 10.1016/j.bmcl.2018.02.039. Epub 2018 Feb 21. Bioorg Med Chem Lett. 2018. PMID: 29548573

2

HIV-1 protease inhibitors based on hydroxyethylene dipeptide isosteres: an investigation into the role of the P1' side chain on structure-activity.

Young SD, Payne LS, Thompson WJ, Gaffin N, Lyle TA, Britcher SF, Graham SL, Schultz TH, Deana AA, Darke PL, et al. Young SD, et al. Among authors: graham sl. J Med Chem. 1992 May 15;35(10):1702-9. doi: 10.1021/jm00088a004. J Med Chem. 1992. PMID: 1588552

3

Topically active carbonic anhydrase inhibitors. 4. [(Hydroxyalkyl)sulfonyl]benzene and [(hydroxyalkyl)sulfonyl]thiophenesulfonamides.

Shepard KL, Graham SL, Hudcosky RJ, Michelson SR, Scholz TH, Schwam H, Smith AM, Sondey JM, Strohmaier KM, Smith RL, et al. Shepard KL, et al. Among authors: graham sl. J Med Chem. 1991 Oct;34(10):3098-105. doi: 10.1021/jm00114a020. J Med Chem. 1991. PMID: 1920359

4

Topically active carbonic anhydrase inhibitors. 2. Benzo[b]thiophenesulfonamide derivatives with ocular hypotensive activity.

Graham SL, Shepard KL, Anderson PS, Baldwin JJ, Best DB, Christy ME, Freedman MB, Gautheron P, Habecker CN, Hoffman JM, et al. Graham SL, et al. J Med Chem. 1989 Dec;32(12):2548-54. doi: 10.1021/jm00132a009. J Med Chem. 1989. PMID: 2585443

5

Synthesis and biological activity of ras farnesyl protein transferase inhibitors. Tetrapeptide analogs with amino methyl and carbon linkages.

Wai JS, Bamberger DL, Fisher TE, Graham SL, Smith RL, Gibbs JB, Mosser SD, Oliff AI, Pompliano DL, Rands E, et al. Wai JS, et al. Among authors: graham sl. Bioorg Med Chem. 1994 Sep;2(9):939-47. doi: 10.1016/s0968-0896(00)82043-x. Bioorg Med Chem. 1994. PMID: 7712129

6

Pseudopeptide inhibitors of Ras farnesyl-protein transferase.

Graham SL, deSolms SJ, Giuliani EA, Kohl NE, Mosser SD, Oliff AI, Pompliano DL, Rands E, Breslin MJ, Deana AA, et al. Graham SL, et al. J Med Chem. 1994 Mar 18;37(6):725-32. doi: 10.1021/jm00032a004. J Med Chem. 1994. PMID: 8145221

7

Sulfonylmethanesulfonamide inhibitors of carbonic anhydrase.

Scholz TH, Sondey JM, Randall WC, Schwam H, Thompson WJ, Mallorga PJ, Sugrue MF, Graham SL. Scholz TH, et al. Among authors: graham sl. J Med Chem. 1993 Jul 23;36(15):2134-41. doi: 10.1021/jm00067a012. J Med Chem. 1993. PMID: 8340917

8

N-Arylalkyl pseudopeptide inhibitors of farnesyltransferase.

deSolms SJ, Giuliani EA, Graham SL, Koblan KS, Kohl NE, Mosser SD, Oliff AI, Pompliano DL, Rands E, Scholz TH, Wiscount CM, Gibbs JB, Smith RL. deSolms SJ, et al. Among authors: graham sl. J Med Chem. 1998 Jul 2;41(14):2651-6. doi: 10.1021/jm9800907. J Med Chem. 1998. PMID: 9651171

9

Potent, non-thiol inhibitors of farnesyltransferase.

Breslin MJ, deSolms SJ, Giuliani EA, Stokker GE, Graham SL, Pompliano DL, Mosser SD, Hamilton KA, Hutchinson JH. Breslin MJ, et al. Among authors: graham sl. Bioorg Med Chem Lett. 1998 Dec 1;8(23):3311-6. doi: 10.1016/s0960-894x(98)00586-1. Bioorg Med Chem Lett. 1998. PMID: 9873725

10

Non-thiol 3-aminomethylbenzamide inhibitors of farnesyl-protein transferase.

Ciccarone TM, MacTough SC, Williams TM, Dinsmore CJ, O'Neill TJ, Shah D, Culberson JC, Koblan KS, Kohl NE, Gibbs JB, Oliff AI, Graham SL, Hartman GD. Ciccarone TM, et al. Among authors: graham sl. Bioorg Med Chem Lett. 1999 Jul 19;9(14):1991-6. doi: 10.1016/s0960-894x(99)00323-6. Bioorg Med Chem Lett. 1999. PMID: 10450968

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