Loughery JEP - Search Results

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Depletion of DNMT1 in differentiated human cells highlights key classes of sensitive genes and an interplay with polycomb repression.

O'Neill KM, Irwin RE, Mackin SJ, Thursby SJ, Thakur A, Bertens C, Masala L, Loughery JEP, McArt DG, Walsh CP. O'Neill KM, et al. Among authors: loughery jep. Epigenetics Chromatin. 2018 Mar 29;11(1):12. doi: 10.1186/s13072-018-0182-4. Epigenetics Chromatin. 2018. PMID: 29598829 Free PMC article.

DNMT1 deficiency triggers mismatch repair defects in human cells through depletion of repair protein levels in a process involving the DNA damage response.

Loughery JE, Dunne PD, O'Neill KM, Meehan RR, McDaid JR, Walsh CP. Loughery JE, et al. Hum Mol Genet. 2011 Aug 15;20(16):3241-55. doi: 10.1093/hmg/ddr236. Epub 2011 Jun 2. Hum Mol Genet. 2011. PMID: 21636528

MLH1 mediates PARP-dependent cell death in response to the methylating agent N-methyl-N-nitrosourea.

McDaid JR, Loughery J, Dunne P, Boyer JC, Downes CS, Farber RA, Walsh CP. McDaid JR, et al. Br J Cancer. 2009 Aug 4;101(3):441-51. doi: 10.1038/sj.bjc.6605186. Epub 2009 Jul 21. Br J Cancer. 2009. PMID: 19623177 Free PMC article.

Critical role for p53-serine 15 phosphorylation in stimulating transactivation at p53-responsive promoters.

Loughery J, Cox M, Smith LM, Meek DW. Loughery J, et al. Nucleic Acids Res. 2014 Jul;42(12):7666-80. doi: 10.1093/nar/gku501. Epub 2014 Jun 13. Nucleic Acids Res. 2014. PMID: 24928858 Free PMC article.

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