O'Neill KM - Search Results

1

Depletion of DNMT1 in differentiated human cells highlights key classes of sensitive genes and an interplay with polycomb repression.

O'Neill KM, Irwin RE, Mackin SJ, Thursby SJ, Thakur A, Bertens C, Masala L, Loughery JEP, McArt DG, Walsh CP. O'Neill KM, et al. Epigenetics Chromatin. 2018 Mar 29;11(1):12. doi: 10.1186/s13072-018-0182-4. Epigenetics Chromatin. 2018. PMID: 29598829 Free PMC article.

2

DNMT1 deficiency triggers mismatch repair defects in human cells through depletion of repair protein levels in a process involving the DNA damage response.

Loughery JE, Dunne PD, O'Neill KM, Meehan RR, McDaid JR, Walsh CP. Loughery JE, et al. Hum Mol Genet. 2011 Aug 15;20(16):3241-55. doi: 10.1093/hmg/ddr236. Epub 2011 Jun 2. Hum Mol Genet. 2011. PMID: 21636528

3

Ontogeny, conservation and functional significance of maternally inherited DNA methylation at two classes of non-imprinted genes.

Rutledge CE, Thakur A, O'Neill KM, Irwin RE, Sato S, Hata K, Walsh CP. Rutledge CE, et al. Development. 2014 Mar;141(6):1313-23. doi: 10.1242/dev.104646. Epub 2014 Feb 12. Development. 2014. PMID: 24523459 Free PMC article.

4

5-Hydroxymethylation marks a class of neuronal gene regulated by intragenic methylcytosine levels.

Irwin RE, Thakur A, O' Neill KM, Walsh CP. Irwin RE, et al. Genomics. 2014 Nov;104(5):383-92. doi: 10.1016/j.ygeno.2014.08.013. Epub 2014 Aug 29. Genomics. 2014. PMID: 25179375 Free article.

5

Regulation of miR-200c and miR-141 by Methylation in Prostate Cancer.

Lynch SM, O'Neill KM, McKenna MM, Walsh CP, McKenna DJ. Lynch SM, et al. Prostate. 2016 Sep;76(13):1146-59. doi: 10.1002/pros.23201. Epub 2016 May 16. Prostate. 2016. PMID: 27198154 Free PMC article.

6

Widespread recovery of methylation at gametic imprints in hypomethylated mouse stem cells following rescue with DNMT3A2.

Thakur A, Mackin SJ, Irwin RE, O'Neill KM, Pollin G, Walsh C. Thakur A, et al. Epigenetics Chromatin. 2016 Nov 22;9:53. doi: 10.1186/s13072-016-0104-2. eCollection 2016. Epigenetics Chromatin. 2016. PMID: 27895716 Free PMC article.

7

Comparison of DNMT1 inhibitors by methylome profiling identifies unique signature of 5-aza-2'deoxycytidine.

Mackin SJ, O'Neill KM, Walsh CP. Mackin SJ, et al. Epigenomics. 2018 Aug;10(8):1085-1101. doi: 10.2217/epi-2017-0171. Epub 2018 Aug 2. Epigenomics. 2018. PMID: 30070602

8

Epigenetic Regulation of Endothelial Cell Function by Nucleic Acid Methylation in Cardiac Homeostasis and Disease.

Russell-Hallinan A, Watson CJ, O'Dwyer D, Grieve DJ, O'Neill KM. Russell-Hallinan A, et al. Cardiovasc Drugs Ther. 2021 Oct;35(5):1025-1044. doi: 10.1007/s10557-020-07019-4. Cardiovasc Drugs Ther. 2021. PMID: 32748033 Free PMC article. Review.

9

Signalling mechanisms underlying doxorubicin and Nox2 NADPH oxidase-induced cardiomyopathy: involvement of mitofusin-2.

McLaughlin D, Zhao Y, O'Neill KM, Edgar KS, Dunne PD, Kearney AM, Grieve DJ, McDermott BJ. McLaughlin D, et al. Br J Pharmacol. 2017 Nov;174(21):3677-3695. doi: 10.1111/bph.13773. Epub 2017 Apr 22. Br J Pharmacol. 2017. PMID: 28261787 Free PMC article.

10

Enhanced Function of Induced Pluripotent Stem Cell-Derived Endothelial Cells Through ESM1 Signaling.

Vilà-González M, Kelaini S, Magee C, Caines R, Campbell D, Eleftheriadou M, Cochrane A, Drehmer D, Tsifaki M, O'Neill K, Pedrini E, Yang C, Medina R, McDonald D, Simpson D, Zampetaki A, Zeng L, Grieve D, Lois N, Stitt AW, Margariti A. Vilà-González M, et al. Stem Cells. 2019 Feb;37(2):226-239. doi: 10.1002/stem.2936. Epub 2018 Nov 17. Stem Cells. 2019. PMID: 30372556 Free PMC article.

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