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Response to ERBB3-Directed Targeted Therapy in NRG1-Rearranged Cancers.
Cancer Discov. 2018 Jun;8(6):686-695. doi: 10.1158/2159-8290.CD-17-1004. Epub 2018 Apr 2.
Cancer Discov. 2018.
PMID: 29610121
Free PMC article.
Clinical Trial.
High-Throughput Screening and Triage Assays Identify Small Molecules Targeting c-MYC in Cancer Cells.
Kallal LA, Waszkiewicz A, Jaworski JP, Della Pietra A, Berrodin T, Brady P, Jurewicz AJ, Zeng X, Payne L, Medina JR, Doepner-Buser C, Mangatt B.
Kallal LA, et al.
SLAS Discov. 2021 Feb;26(2):216-229. doi: 10.1177/2472555220985457.
SLAS Discov. 2021.
PMID: 33482073
Free article.
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Cell-Based Drug Discovery: Identification and Optimization of Small Molecules that Reduce c-MYC Protein Levels in Cells.
Medina JR, Tian X, Li WH, Suarez D, Mack JF, LaFrance L, Martyr C, Brackley J, Di Marco C, Rivero R, Heerding DA, McHugh C, Minthorn E, Bhaskar A, Rubin J, Butticello M, Carpenter C, Nartey EN, Berrodin TJ, Kallal LA, Mangatt B.
Medina JR, et al.
J Med Chem. 2021 Nov 11;64(21):16056-16087. doi: 10.1021/acs.jmedchem.1c01416. Epub 2021 Oct 20.
J Med Chem. 2021.
PMID: 34669409
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Identification and Optimization of Novel Small c-Abl Kinase Activators Using Fragment and HTS Methodologies.
Simpson GL, Bertrand SM, Borthwick JA, Campobasso N, Chabanet J, Chen S, Coggins J, Cottom J, Christensen SB, Dawson HC, Evans HL, Hobbs AN, Hong X, Mangatt B, Munoz-Muriedas J, Oliff A, Qin D, Scott-Stevens P, Ward P, Washio Y, Yang J, Young RJ.
Simpson GL, et al.
J Med Chem. 2019 Feb 28;62(4):2154-2171. doi: 10.1021/acs.jmedchem.8b01872. Epub 2019 Feb 11.
J Med Chem. 2019.
PMID: 30689376
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