Tramarin M - Search Results

1

The antidepressant tianeptine reverts synaptic AMPA receptor defects caused by deficiency of CDKL5.

Tramarin M, Rusconi L, Pizzamiglio L, Barbiero I, Peroni D, Scaramuzza L, Guilliams T, Cavalla D, Antonucci F, Kilstrup-Nielsen C. Tramarin M, et al. Hum Mol Genet. 2018 Jun 15;27(12):2052-2063. doi: 10.1093/hmg/ddy108. Hum Mol Genet. 2018. PMID: 29618004

2

Synaptic synthesis, dephosphorylation, and degradation: a novel paradigm for an activity-dependent neuronal control of CDKL5.

La Montanara P, Rusconi L, Locarno A, Forti L, Barbiero I, Tramarin M, Chandola C, Kilstrup-Nielsen C, Landsberger N. La Montanara P, et al. Among authors: tramarin m. J Biol Chem. 2015 Feb 13;290(7):4512-27. doi: 10.1074/jbc.M114.589762. Epub 2015 Jan 2. J Biol Chem. 2015. PMID: 25555910 Free PMC article.

3

The neurosteroid pregnenolone reverts microtubule derangement induced by the loss of a functional CDKL5-IQGAP1 complex.

Barbiero I, Peroni D, Tramarin M, Chandola C, Rusconi L, Landsberger N, Kilstrup-Nielsen C. Barbiero I, et al. Among authors: tramarin m. Hum Mol Genet. 2017 Sep 15;26(18):3520-3530. doi: 10.1093/hmg/ddx237. Hum Mol Genet. 2017. PMID: 28641386

4

CDKL5 localizes at the centrosome and midbody and is required for faithful cell division.

Barbiero I, Valente D, Chandola C, Magi F, Bergo A, Monteonofrio L, Tramarin M, Fazzari M, Soddu S, Landsberger N, Rinaldo C, Kilstrup-Nielsen C. Barbiero I, et al. Among authors: tramarin m. Sci Rep. 2017 Jul 24;7(1):6228. doi: 10.1038/s41598-017-05875-z. Sci Rep. 2017. PMID: 28740074 Free PMC article.

5

Cannabidivarin completely rescues cognitive deficits and delays neurological and motor defects in male Mecp2 mutant mice.

Zamberletti E, Gabaglio M, Piscitelli F, Brodie JS, Woolley-Roberts M, Barbiero I, Tramarin M, Binelli G, Landsberger N, Kilstrup-Nielsen C, Rubino T, Di Marzo V, Parolaro D. Zamberletti E, et al. Among authors: tramarin m. J Psychopharmacol. 2019 Jul;33(7):894-907. doi: 10.1177/0269881119844184. Epub 2019 May 14. J Psychopharmacol. 2019. PMID: 31084246 Free article.

6

Pregnenolone and pregnenolone-methyl-ether rescue neuronal defects caused by dysfunctional CLIP170 in a neuronal model of CDKL5 Deficiency Disorder.

Barbiero I, Peroni D, Siniscalchi P, Rusconi L, Tramarin M, De Rosa R, Motta P, Bianchi M, Kilstrup-Nielsen C. Barbiero I, et al. Among authors: tramarin m. Neuropharmacology. 2020 Mar 1;164:107897. doi: 10.1016/j.neuropharm.2019.107897. Epub 2019 Nov 30. Neuropharmacology. 2020. PMID: 31794725

7

The green tea polyphenol epigallocatechin-3-gallate (EGCG) restores CDKL5-dependent synaptic defects in vitro and in vivo.

Trovò L, Fuchs C, De Rosa R, Barbiero I, Tramarin M, Ciani E, Rusconi L, Kilstrup-Nielsen C. Trovò L, et al. Among authors: tramarin m. Neurobiol Dis. 2020 May;138:104791. doi: 10.1016/j.nbd.2020.104791. Epub 2020 Feb 4. Neurobiol Dis. 2020. PMID: 32032735 Free PMC article.

8

Pregnenolone-methyl-ether enhances CLIP170 and microtubule functions improving spine maturation and hippocampal deficits related to CDKL5 deficiency.

Barbiero I, Zamberletti E, Tramarin M, Gabaglio M, Peroni D, De Rosa R, Baldin S, Bianchi M, Rubino T, Kilstrup-Nielsen C. Barbiero I, et al. Among authors: tramarin m. Hum Mol Genet. 2022 Aug 23;31(16):2738-2750. doi: 10.1093/hmg/ddac067. Hum Mol Genet. 2022. PMID: 35348691

9

Loss of CDKL5 Causes Synaptic GABAergic Defects That Can Be Restored with the Neuroactive Steroid Pregnenolone-Methyl-Ether.

De Rosa R, Valastro S, Cambria C, Barbiero I, Puricelli C, Tramarin M, Randi S, Bianchi M, Antonucci F, Kilstrup-Nielsen C. De Rosa R, et al. Among authors: tramarin m. Int J Mol Sci. 2022 Dec 21;24(1):68. doi: 10.3390/ijms24010068. Int J Mol Sci. 2022. PMID: 36613509 Free PMC article.

10

Genicular Artery Embolization: A New Tool for the Management of Refractory Osteoarthritis-Related Knee Pain.

Femia M, Valenti Pittino C, Fumarola EM, Tramarin M, Papa M, Giurazza F, Francioso AP, Fior D, Moramarco LP, Antonini G, Vercelli R, Cariati M. Femia M, et al. Among authors: tramarin m. J Pers Med. 2024 Jun 26;14(7):686. doi: 10.3390/jpm14070686. J Pers Med. 2024. PMID: 39063940 Free PMC article. Review.

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