Wexler RR - Search Results

1

Correction to "Atropisomer Control in Macrocyclic Factor VIIa Inhibitors".

Glunz PW, Mueller L, Cheney DL, Ladziata V, Zou Y, Wurtz NR, Wei A, Wong PC, Wexler RR, Priestley ES. Glunz PW, et al. Among authors: wexler rr. J Med Chem. 2018 Apr 26;61(8):3752. doi: 10.1021/acs.jmedchem.8b00465. Epub 2018 Apr 5. J Med Chem. 2018. PMID: 29620363 No abstract available.

2

Balanced AT1/AT2 receptor antagonists. 4. XR510 and related 5-(3-amidopropanoyl)imidazoles possessing equal affinity for the AT1 and AT2 receptors.

Quan ML, Chiu AT, Ellis CD, Wong PC, Wexler RR, Timmermans PB. Quan ML, et al. Among authors: wexler rr. J Med Chem. 1995 Jul 21;38(15):2938-45. doi: 10.1021/jm00015a016. J Med Chem. 1995. PMID: 7636854

3

Preparation of meta-amidino-N,N-disubstituted anilines as potent inhibitors of coagulation factor Xa.

Fevig JM, Cacciola J, Alexander RS, Knabb RM, Lam GN, Wong PC, Wexler RR. Fevig JM, et al. Among authors: wexler rr. Bioorg Med Chem Lett. 1998 Nov 17;8(22):3143-8. doi: 10.1016/s0960-894x(98)00574-5. Bioorg Med Chem Lett. 1998. PMID: 9873692

4

Design and synthesis of potent and selective 5,6-fused heterocyclic thrombin inhibitors.

Dominguez C, Duffy DE, Han Q, Alexander RS, Galemmo RA Jr, Park JM, Wong PC, Amparo EC, Knabb RM, Luettgen J, Wexler RR. Dominguez C, et al. Among authors: wexler rr. Bioorg Med Chem Lett. 1999 Apr 5;9(7):925-30. doi: 10.1016/s0960-894x(99)00113-4. Bioorg Med Chem Lett. 1999. PMID: 10230612

5

Preparation of pyrrolidine and isoxazolidine benzamidines as potent inhibitors of coagulation factor Xa.

Fevig JM, Buriak J Jr, Stouten PF, Knabb RM, Lam GN, Wong PC, Wexler RR. Fevig JM, et al. Among authors: wexler rr. Bioorg Med Chem Lett. 1999 Apr 19;9(8):1195-200. doi: 10.1016/s0960-894x(99)00164-x. Bioorg Med Chem Lett. 1999. PMID: 10328312

6

Design and synthesis of isoxazoline derivatives as factor Xa inhibitors. 1.

Quan ML, Liauw AY, Ellis CD, Pruitt JR, Carini DJ, Bostrom LL, Huang PP, Harrison K, Knabb RM, Thoolen MJ, Wong PC, Wexler RR. Quan ML, et al. Among authors: wexler rr. J Med Chem. 1999 Jul 29;42(15):2752-9. doi: 10.1021/jm980405i. J Med Chem. 1999. PMID: 10425086

7

Design and synthesis of isoxazoline derivatives as factor Xa inhibitors. 2.

Quan ML, Ellis CD, Liauw AY, Alexander RS, Knabb RM, Lam G, Wright MR, Wong PC, Wexler RR. Quan ML, et al. Among authors: wexler rr. J Med Chem. 1999 Jul 29;42(15):2760-73. doi: 10.1021/jm980406a. J Med Chem. 1999. PMID: 10425087

8

The de novo design and synthesis of cyclic urea inhibitors of factor Xa: optimization of the S4 ligand.

Galemmo RA Jr, Wells BL, Rossi KA, Alexander RS, Dominguez C, Maduskuie TP, Stouten PF, Wright MR, Aungst BJ, Wong PC, Knabb RM, Wexler RR. Galemmo RA Jr, et al. Among authors: wexler rr. Bioorg Med Chem Lett. 2000 Feb 7;10(3):301-4. doi: 10.1016/s0960-894x(99)00688-5. Bioorg Med Chem Lett. 2000. PMID: 10698459

9

Isoxazolines and isoxazoles as factor Xa inhibitors.

Pruitt JR, Pinto DJ, Estrella MJ, Bostrom LL, Knabb RM, Wong PC, Wright MR, Wexler RR. Pruitt JR, et al. Among authors: wexler rr. Bioorg Med Chem Lett. 2000 Apr 17;10(8):685-9. doi: 10.1016/s0960-894x(00)00097-4. Bioorg Med Chem Lett. 2000. PMID: 10782664

10

Design, synthesis, and biological evaluation of potent and selective amidino bicyclic factor Xa inhibitors.

Han Q, Dominguez C, Stouten PF, Park JM, Duffy DE, Galemmo RA Jr, Rossi KA, Alexander RS, Smallwood AM, Wong PC, Wright MM, Luettgen JM, Knabb RM, Wexler RR. Han Q, et al. Among authors: wexler rr. J Med Chem. 2000 Nov 16;43(23):4398-415. doi: 10.1021/jm000113t. J Med Chem. 2000. PMID: 11087565

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