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Pathogenic Germline Variants in 10,389 Adult Cancers.
Huang KL, Mashl RJ, Wu Y, Ritter DI, Wang J, Oh C, Paczkowska M, Reynolds S, Wyczalkowski MA, Oak N, Scott AD, Krassowski M, Cherniack AD, Houlahan KE, Jayasinghe R, Wang LB, Zhou DC, Liu D, Cao S, Kim YW, Koire A, McMichael JF, Hucthagowder V, Kim TB, Hahn A, Wang C, McLellan MD, Al-Mulla F, Johnson KJ; Cancer Genome Atlas Research Network; Lichtarge O, Boutros PC, Raphael B, Lazar AJ, Zhang W, Wendl MC, Govindan R, Jain S, Wheeler D, Kulkarni S, Dipersio JF, Reimand J, Meric-Bernstam F, Chen K, Shmulevich I, Plon SE, Chen F, Ding L. Huang KL, et al. Among authors: jain s. Cell. 2018 Apr 5;173(2):355-370.e14. doi: 10.1016/j.cell.2018.03.039. Cell. 2018. PMID: 29625052 Free PMC article.
Traditional and targeted exome sequencing reveals common, rare and novel functional deleterious variants in RET-signaling complex in a cohort of living US patients with urinary tract malformations.
Chatterjee R, Ramos E, Hoffman M, VanWinkle J, Martin DR, Davis TK, Hoshi M, Hmiel SP, Beck A, Hruska K, Coplen D, Liapis H, Mitra R, Druley T, Austin P, Jain S. Chatterjee R, et al. Among authors: jain s. Hum Genet. 2012 Nov;131(11):1725-38. doi: 10.1007/s00439-012-1181-3. Epub 2012 Jun 23. Hum Genet. 2012. PMID: 22729463 Free PMC article.
Neurturin-mediated ret activation is required for retinal function.
Brantley MA Jr, Jain S, Barr EE, Johnson EM Jr, Milbrandt J. Brantley MA Jr, et al. Among authors: jain s. J Neurosci. 2008 Apr 16;28(16):4123-35. doi: 10.1523/JNEUROSCI.0249-08.2008. J Neurosci. 2008. PMID: 18417692 Free PMC article.
Etv4 and Etv5 are required downstream of GDNF and Ret for kidney branching morphogenesis.
Lu BC, Cebrian C, Chi X, Kuure S, Kuo R, Bates CM, Arber S, Hassell J, MacNeil L, Hoshi M, Jain S, Asai N, Takahashi M, Schmidt-Ott KM, Barasch J, D'Agati V, Costantini F. Lu BC, et al. Among authors: jain s. Nat Genet. 2009 Dec;41(12):1295-302. doi: 10.1038/ng.476. Epub 2009 Nov 8. Nat Genet. 2009. PMID: 19898483 Free PMC article.
10,901 results
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