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L1 retrotransposition is a common feature of mammalian hepatocarcinogenesis.
Schauer SN, Carreira PE, Shukla R, Gerhardt DJ, Gerdes P, Sanchez-Luque FJ, Nicoli P, Kindlova M, Ghisletti S, Santos AD, Rapoud D, Samuel D, Faivre J, Ewing AD, Richardson SR, Faulkner GJ. Schauer SN, et al. Among authors: faulkner gj. Genome Res. 2018 May;28(5):639-653. doi: 10.1101/gr.226993.117. Epub 2018 Apr 11. Genome Res. 2018. PMID: 29643204 Free PMC article.
Somatic retrotransposition alters the genetic landscape of the human brain.
Baillie JK, Barnett MW, Upton KR, Gerhardt DJ, Richmond TA, De Sapio F, Brennan PM, Rizzu P, Smith S, Fell M, Talbot RT, Gustincich S, Freeman TC, Mattick JS, Hume DA, Heutink P, Carninci P, Jeddeloh JA, Faulkner GJ. Baillie JK, et al. Among authors: faulkner gj. Nature. 2011 Oct 30;479(7374):534-7. doi: 10.1038/nature10531. Nature. 2011. PMID: 22037309 Free PMC article.
Extensive somatic L1 retrotransposition in colorectal tumors.
Solyom S, Ewing AD, Rahrmann EP, Doucet T, Nelson HH, Burns MB, Harris RS, Sigmon DF, Casella A, Erlanger B, Wheelan S, Upton KR, Shukla R, Faulkner GJ, Largaespada DA, Kazazian HH Jr. Solyom S, et al. Among authors: faulkner gj. Genome Res. 2012 Dec;22(12):2328-38. doi: 10.1101/gr.145235.112. Epub 2012 Sep 11. Genome Res. 2012. PMID: 22968929 Free PMC article.
Endogenous retrotransposition activates oncogenic pathways in hepatocellular carcinoma.
Shukla R, Upton KR, Muñoz-Lopez M, Gerhardt DJ, Fisher ME, Nguyen T, Brennan PM, Baillie JK, Collino A, Ghisletti S, Sinha S, Iannelli F, Radaelli E, Dos Santos A, Rapoud D, Guettier C, Samuel D, Natoli G, Carninci P, Ciccarelli FD, Garcia-Perez JL, Faivre J, Faulkner GJ. Shukla R, et al. Among authors: faulkner gj. Cell. 2013 Mar 28;153(1):101-11. doi: 10.1016/j.cell.2013.02.032. Cell. 2013. PMID: 23540693 Free PMC article.
L1 retrotransposons, cancer stem cells and oncogenesis.
Carreira PE, Richardson SR, Faulkner GJ. Carreira PE, et al. Among authors: faulkner gj. FEBS J. 2014 Jan;281(1):63-73. doi: 10.1111/febs.12601. Epub 2013 Nov 28. FEBS J. 2014. PMID: 24286172 Free PMC article. Review.
L1 retrotransposons and somatic mosaicism in the brain.
Richardson SR, Morell S, Faulkner GJ. Richardson SR, et al. Among authors: faulkner gj. Annu Rev Genet. 2014;48:1-27. doi: 10.1146/annurev-genet-120213-092412. Epub 2014 Jul 14. Annu Rev Genet. 2014. PMID: 25036377 Review.
Ubiquitous L1 mosaicism in hippocampal neurons.
Upton KR, Gerhardt DJ, Jesuadian JS, Richardson SR, Sánchez-Luque FJ, Bodea GO, Ewing AD, Salvador-Palomeque C, van der Knaap MS, Brennan PM, Vanderver A, Faulkner GJ. Upton KR, et al. Among authors: faulkner gj. Cell. 2015 Apr 9;161(2):228-39. doi: 10.1016/j.cell.2015.03.026. Cell. 2015. PMID: 25860606 Free PMC article.
Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells.
Klawitter S, Fuchs NV, Upton KR, Muñoz-Lopez M, Shukla R, Wang J, Garcia-Cañadas M, Lopez-Ruiz C, Gerhardt DJ, Sebe A, Grabundzija I, Merkert S, Gerdes P, Pulgarin JA, Bock A, Held U, Witthuhn A, Haase A, Sarkadi B, Löwer J, Wolvetang EJ, Martin U, Ivics Z, Izsvák Z, Garcia-Perez JL, Faulkner GJ, Schumann GG. Klawitter S, et al. Among authors: faulkner gj. Nat Commun. 2016 Jan 8;7:10286. doi: 10.1038/ncomms10286. Nat Commun. 2016. PMID: 26743714 Free PMC article.
97 results