Walker S - Search Results

1

Genome-wide mutant profiling predicts the mechanism of a Lipid II binding antibiotic.

Santiago M, Lee W, Fayad AA, Coe KA, Rajagopal M, Do T, Hennessen F, Srisuknimit V, Müller R, Meredith TC, Walker S. Santiago M, et al. Among authors: walker s. Nat Chem Biol. 2018 Jun;14(6):601-608. doi: 10.1038/s41589-018-0041-4. Epub 2018 Apr 16. Nat Chem Biol. 2018. PMID: 29662210 Free PMC article.

2

Differential inhibition of Staphylococcus aureus PBP2 by glycopeptide antibiotics.

Leimkuhler C, Chen L, Barrett D, Panzone G, Sun B, Falcone B, Oberthür M, Donadio S, Walker S, Kahne D. Leimkuhler C, et al. Among authors: walker s. J Am Chem Soc. 2005 Mar 16;127(10):3250-1. doi: 10.1021/ja043849e. J Am Chem Soc. 2005. PMID: 15755121

3

Synthesis of heptaprenyl-lipid IV to analyze peptidoglycan glycosyltransferases.

Zhang Y, Fechter EJ, Wang TS, Barrett D, Walker S, Kahne DE. Zhang Y, et al. Among authors: walker s. J Am Chem Soc. 2007 Mar 21;129(11):3080-1. doi: 10.1021/ja069060g. Epub 2007 Feb 27. J Am Chem Soc. 2007. PMID: 17323951 Free PMC article.

4

A revised pathway proposed for Staphylococcus aureus wall teichoic acid biosynthesis based on in vitro reconstitution of the intracellular steps.

Brown S, Zhang YH, Walker S. Brown S, et al. Among authors: walker s. Chem Biol. 2008 Jan;15(1):12-21. doi: 10.1016/j.chembiol.2007.11.011. Chem Biol. 2008. PMID: 18215769 Free PMC article.

5

Late-stage polyribitol phosphate wall teichoic acid biosynthesis in Staphylococcus aureus.

Meredith TC, Swoboda JG, Walker S. Meredith TC, et al. Among authors: walker s. J Bacteriol. 2008 Apr;190(8):3046-56. doi: 10.1128/JB.01880-07. Epub 2008 Feb 15. J Bacteriol. 2008. PMID: 18281399 Free PMC article.

6

Structural analysis of the contacts anchoring moenomycin to peptidoglycan glycosyltransferases and implications for antibiotic design.

Yuan Y, Fuse S, Ostash B, Sliz P, Kahne D, Walker S. Yuan Y, et al. Among authors: walker s. ACS Chem Biol. 2008 Jul 18;3(7):429-36. doi: 10.1021/cb800078a. ACS Chem Biol. 2008. PMID: 18642800 Free PMC article.

7

Discovery of a small molecule that blocks wall teichoic acid biosynthesis in Staphylococcus aureus.

Swoboda JG, Meredith TC, Campbell J, Brown S, Suzuki T, Bollenbach T, Malhowski AJ, Kishony R, Gilmore MS, Walker S. Swoboda JG, et al. Among authors: walker s. ACS Chem Biol. 2009 Oct 16;4(10):875-83. doi: 10.1021/cb900151k. ACS Chem Biol. 2009. PMID: 19689117 Free PMC article.

8

Wall teichoic acid function, biosynthesis, and inhibition.

Swoboda JG, Campbell J, Meredith TC, Walker S. Swoboda JG, et al. Among authors: walker s. Chembiochem. 2010 Jan 4;11(1):35-45. doi: 10.1002/cbic.200900557. Chembiochem. 2010. PMID: 19899094 Free PMC article. Review. No abstract available.

9

Functional and structural analysis of a key region of the cell wall inhibitor moenomycin.

Fuse S, Tsukamoto H, Yuan Y, Wang TS, Zhang Y, Bolla M, Walker S, Sliz P, Kahne D. Fuse S, et al. Among authors: walker s. ACS Chem Biol. 2010 Jul 16;5(7):701-11. doi: 10.1021/cb100048q. ACS Chem Biol. 2010. PMID: 20496948 Free PMC article.

10

Staphylococcus aureus and Bacillus subtilis W23 make polyribitol wall teichoic acids using different enzymatic pathways.

Brown S, Meredith T, Swoboda J, Walker S. Brown S, et al. Among authors: walker s. Chem Biol. 2010 Oct 29;17(10):1101-10. doi: 10.1016/j.chembiol.2010.07.017. Chem Biol. 2010. PMID: 21035733 Free PMC article.

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