Charrier S - Search Results

1

Non-Clinical Efficacy and Safety Studies on G1XCGD, a Lentiviral Vector for Ex Vivo Gene Therapy of X-Linked Chronic Granulomatous Disease.

Brendel C, Rothe M, Santilli G, Charrier S, Stein S, Kunkel H, Abriss D, Müller-Kuller U, Gaspar B, Modlich U, Galy A, Schambach A, Thrasher AJ, Grez M. Brendel C, et al. Among authors: charrier s. Hum Gene Ther Clin Dev. 2018 Jun;29(2):69-79. doi: 10.1089/humc.2017.245. Epub 2018 Apr 17. Hum Gene Ther Clin Dev. 2018. PMID: 29664709

2

Preclinical Development of a Lentiviral Vector for Gene Therapy of X-Linked Severe Combined Immunodeficiency.

Poletti V, Charrier S, Corre G, Gjata B, Vignaud A, Zhang F, Rothe M, Schambach A, Gaspar HB, Thrasher AJ, Mavilio F. Poletti V, et al. Among authors: charrier s. Mol Ther Methods Clin Dev. 2018 Mar 10;9:257-269. doi: 10.1016/j.omtm.2018.03.002. eCollection 2018 Jun 15. Mol Ther Methods Clin Dev. 2018. PMID: 29707600 Free PMC article.

3

A lentiviral vector encoding the human Wiskott-Aldrich syndrome protein corrects immune and cytoskeletal defects in WASP knockout mice.

Charrier S, Stockholm D, Seye K, Opolon P, Taveau M, Gross DA, Bucher-Laurent S, Delenda C, Vainchenker W, Danos O, Galy A. Charrier S, et al. Gene Ther. 2005 Apr;12(7):597-606. doi: 10.1038/sj.gt.3302440. Gene Ther. 2005. PMID: 15616597

4

Lentiviral vectors targeting WASp expression to hematopoietic cells, efficiently transduce and correct cells from WAS patients.

Charrier S, Dupré L, Scaramuzza S, Jeanson-Leh L, Blundell MP, Danos O, Cattaneo F, Aiuti A, Eckenberg R, Thrasher AJ, Roncarolo MG, Galy A. Charrier S, et al. Gene Ther. 2007 Mar;14(5):415-28. doi: 10.1038/sj.gt.3302863. Epub 2006 Oct 19. Gene Ther. 2007. PMID: 17051251

5

Validation of a mutated PRE sequence allowing high and sustained transgene expression while abrogating WHV-X protein synthesis: application to the gene therapy of WAS.

Zanta-Boussif MA, Charrier S, Brice-Ouzet A, Martin S, Opolon P, Thrasher AJ, Hope TJ, Galy A. Zanta-Boussif MA, et al. Among authors: charrier s. Gene Ther. 2009 May;16(5):605-19. doi: 10.1038/gt.2009.3. Epub 2009 Mar 5. Gene Ther. 2009. PMID: 19262615

6

Quantification of lentiviral vector copy numbers in individual hematopoietic colony-forming cells shows vector dose-dependent effects on the frequency and level of transduction.

Charrier S, Ferrand M, Zerbato M, Précigout G, Viornery A, Bucher-Laurent S, Benkhelifa-Ziyyat S, Merten OW, Perea J, Galy A. Charrier S, et al. Gene Ther. 2011 May;18(5):479-87. doi: 10.1038/gt.2010.163. Epub 2010 Dec 16. Gene Ther. 2011. PMID: 21160533 Free PMC article.

7

Diverse genomic integration of a lentiviral vector developed for the treatment of Wiskott-Aldrich syndrome.

Mantovani J, Charrier S, Eckenberg R, Saurin W, Danos O, Perea J, Galy A. Mantovani J, et al. Among authors: charrier s. J Gene Med. 2009 Aug;11(8):645-54. doi: 10.1002/jgm.1346. J Gene Med. 2009. PMID: 19455589

8

Insertional transformation of hematopoietic cells by self-inactivating lentiviral and gammaretroviral vectors.

Modlich U, Navarro S, Zychlinski D, Maetzig T, Knoess S, Brugman MH, Schambach A, Charrier S, Galy A, Thrasher AJ, Bueren J, Baum C. Modlich U, et al. Among authors: charrier s. Mol Ther. 2009 Nov;17(11):1919-28. doi: 10.1038/mt.2009.179. Epub 2009 Aug 11. Mol Ther. 2009. PMID: 19672245 Free PMC article.

9

Large-scale manufacture and characterization of a lentiviral vector produced for clinical ex vivo gene therapy application.

Merten OW, Charrier S, Laroudie N, Fauchille S, Dugué C, Jenny C, Audit M, Zanta-Boussif MA, Chautard H, Radrizzani M, Vallanti G, Naldini L, Noguiez-Hellin P, Galy A. Merten OW, et al. Among authors: charrier s. Hum Gene Ther. 2011 Mar;22(3):343-56. doi: 10.1089/hum.2010.060. Epub 2011 Mar 7. Hum Gene Ther. 2011. PMID: 21043787

10

Pre-clinical Development of a Lentiviral Vector Expressing the Anti-sickling βAS3 Globin for Gene Therapy for Sickle Cell Disease.

Poletti V, Urbinati F, Charrier S, Corre G, Hollis RP, Campo Fernandez B, Martin S, Rothe M, Schambach A, Kohn DB, Mavilio F. Poletti V, et al. Among authors: charrier s. Mol Ther Methods Clin Dev. 2018 Nov 1;11:167-179. doi: 10.1016/j.omtm.2018.10.014. eCollection 2018 Dec 14. Mol Ther Methods Clin Dev. 2018. PMID: 30533448 Free PMC article.

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