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Non-Clinical Efficacy and Safety Studies on G1XCGD, a Lentiviral Vector for Ex Vivo Gene Therapy of X-Linked Chronic Granulomatous Disease.
Brendel C, Rothe M, Santilli G, Charrier S, Stein S, Kunkel H, Abriss D, Müller-Kuller U, Gaspar B, Modlich U, Galy A, Schambach A, Thrasher AJ, Grez M. Brendel C, et al. Among authors: modlich u. Hum Gene Ther Clin Dev. 2018 Jun;29(2):69-79. doi: 10.1089/humc.2017.245. Epub 2018 Apr 17. Hum Gene Ther Clin Dev. 2018. PMID: 29664709
Self-inactivating retroviral vectors with improved RNA processing.
Kraunus J, Schaumann DH, Meyer J, Modlich U, Fehse B, Brandenburg G, von Laer D, Klump H, Schambach A, Bohne J, Baum C. Kraunus J, et al. Among authors: modlich u. Gene Ther. 2004 Nov;11(21):1568-78. doi: 10.1038/sj.gt.3302309. Gene Ther. 2004. PMID: 15372067
Gene therapy: X-SCID transgene leukaemogenicity.
Thrasher AJ, Gaspar HB, Baum C, Modlich U, Schambach A, Candotti F, Otsu M, Sorrentino B, Scobie L, Cameron E, Blyth K, Neil J, Abina SH, Cavazzana-Calvo M, Fischer A. Thrasher AJ, et al. Among authors: modlich u. Nature. 2006 Sep 21;443(7109):E5-6; discussion E6-7. doi: 10.1038/nature05219. Nature. 2006. PMID: 16988659
Importance of murine study design for testing toxicity of retroviral vectors in support of phase I trials.
Will E, Bailey J, Schuesler T, Modlich U, Balcik B, Burzynski B, Witte D, Layh-Schmitt G, Rudolph C, Schlegelberger B, von Kalle C, Baum C, Sorrentino BP, Wagner LM, Kelly P, Reeves L, Williams DA. Will E, et al. Among authors: modlich u. Mol Ther. 2007 Apr;15(4):782-91. doi: 10.1038/sj.mt.6300083. Epub 2007 Feb 13. Mol Ther. 2007. PMID: 17299409 Free article.
[Gene therapy of SCID-X1].
Baum C, Schambach A, Modlich U, Thrasher A. Baum C, et al. Among authors: modlich u. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2007 Dec;50(12):1507-17. doi: 10.1007/s00103-007-0385-5. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2007. PMID: 18046520 Review. German.
83 results