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Page 1
Gene Transfer of Engineered Calmodulin Alleviates Ventricular Arrhythmias in a Calsequestrin-Associated Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia.
Liu B, Walton SD, Ho HT, Belevych AE, Tikunova SB, Bonilla I, Shettigar V, Knollmann BC, Priori SG, Volpe P, Radwański PB, Davis JP, Györke S. Liu B, et al. Among authors: shettigar v. J Am Heart Assoc. 2018 May 2;7(10):e008155. doi: 10.1161/JAHA.117.008155. J Am Heart Assoc. 2018. PMID: 29720499 Free PMC article.
Designing proteins to combat disease: Cardiac troponin C as an example.
Davis JP, Shettigar V, Tikunova SB, Little SC, Liu B, Siddiqui JK, Janssen PM, Ziolo MT, Walton SD. Davis JP, et al. Among authors: shettigar v. Arch Biochem Biophys. 2016 Jul 1;601:4-10. doi: 10.1016/j.abb.2016.02.007. Epub 2016 Feb 18. Arch Biochem Biophys. 2016. PMID: 26901433 Free PMC article. Review.
Rationally engineered Troponin C modulates in vivo cardiac function and performance in health and disease.
Shettigar V, Zhang B, Little SC, Salhi HE, Hansen BJ, Li N, Zhang J, Roof SR, Ho HT, Brunello L, Lerch JK, Weisleder N, Fedorov VV, Accornero F, Rafael-Fortney JA, Gyorke S, Janssen PM, Biesiadecki BJ, Ziolo MT, Davis JP. Shettigar V, et al. Nat Commun. 2016 Feb 24;7:10794. doi: 10.1038/ncomms10794. Nat Commun. 2016. PMID: 26908229 Free PMC article.
NF-κB inhibition rescues cardiac function by remodeling calcium genes in a Duchenne muscular dystrophy model.
Peterson JM, Wang DJ, Shettigar V, Roof SR, Canan BD, Bakkar N, Shintaku J, Gu JM, Little SC, Ratnam NM, Londhe P, Lu L, Gaw CE, Petrosino JM, Liyanarachchi S, Wang H, Janssen PML, Davis JP, Ziolo MT, Sharma SM, Guttridge DC. Peterson JM, et al. Among authors: shettigar v. Nat Commun. 2018 Aug 24;9(1):3431. doi: 10.1038/s41467-018-05910-1. Nat Commun. 2018. PMID: 30143619 Free PMC article.
TGF-β1 affects cell-cell adhesion in the heart in an NCAM1-dependent mechanism.
Ackermann MA, Petrosino JM, Manring HR, Wright P, Shettigar V, Kilic A, Janssen PML, Ziolo MT, Accornero F. Ackermann MA, et al. Among authors: shettigar v. J Mol Cell Cardiol. 2017 Nov;112:49-57. doi: 10.1016/j.yjmcc.2017.08.015. Epub 2017 Sep 1. J Mol Cell Cardiol. 2017. PMID: 28870505 Free PMC article.
Brown adipose tissue prevents glucose intolerance and cardiac remodeling in high-fat-fed mice after a mild myocardial infarction.
Peres Valgas da Silva C, Shettigar VK, Baer LA, Abay E, Madaris KL, Mehling MR, Hernandez-Saavedra D, Pinckard KM, Seculov NP, Ziolo MT, Stanford KI. Peres Valgas da Silva C, et al. Among authors: shettigar vk. Int J Obes (Lond). 2022 Feb;46(2):350-358. doi: 10.1038/s41366-021-00999-9. Epub 2021 Oct 29. Int J Obes (Lond). 2022. PMID: 34716427 Free PMC article.
Exercise-induced 3'-sialyllactose in breast milk is a critical mediator to improve metabolic health and cardiac function in mouse offspring.
Harris JE, Pinckard KM, Wright KR, Baer LA, Arts PJ, Abay E, Shettigar VK, Lehnig AC, Robertson B, Madaris K, Canova TJ, Sims C, Goodyear LJ, Andres A, Ziolo MT, Bode L, Stanford KI. Harris JE, et al. Among authors: shettigar vk. Nat Metab. 2020 Aug;2(8):678-687. doi: 10.1038/s42255-020-0223-8. Epub 2020 Jun 29. Nat Metab. 2020. PMID: 32694823 Free PMC article.
23 results