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Liberty Asthma QUEST: Phase 3 Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate Dupilumab Efficacy/Safety in Patients with Uncontrolled, Moderate-to-Severe Asthma.
Busse WW, Maspero JF, Rabe KF, Papi A, Wenzel SE, Ford LB, Pavord ID, Zhang B, Staudinger H, Pirozzi G, Amin N, Akinlade B, Eckert L, Chao J, Graham NMH, Teper A. Busse WW, et al. Among authors: wenzel se. Adv Ther. 2018 May;35(5):737-748. doi: 10.1007/s12325-018-0702-4. Epub 2018 May 3. Adv Ther. 2018. PMID: 29725983 Free PMC article. Clinical Trial.
IL4R alpha mutations are associated with asthma exacerbations and mast cell/IgE expression.
Wenzel SE, Balzar S, Ampleford E, Hawkins GA, Busse WW, Calhoun WJ, Castro M, Chung KF, Erzurum S, Gaston B, Israel E, Teague WG, Curran-Everett D, Meyers DA, Bleecker ER. Wenzel SE, et al. Am J Respir Crit Care Med. 2007 Mar 15;175(6):570-6. doi: 10.1164/rccm.200607-909OC. Epub 2006 Dec 14. Am J Respir Crit Care Med. 2007. PMID: 17170387 Free PMC article.
Severe asthma: lessons from the Severe Asthma Research Program.
Wenzel SE, Busse WW; National Heart, Lung, and Blood Institute's Severe Asthma Research Program. Wenzel SE, et al. J Allergy Clin Immunol. 2007 Jan;119(1):14-21; quiz 22-3. doi: 10.1016/j.jaci.2006.10.025. J Allergy Clin Immunol. 2007. PMID: 17208583 Review.
Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program.
Moore WC, Bleecker ER, Curran-Everett D, Erzurum SC, Ameredes BT, Bacharier L, Calhoun WJ, Castro M, Chung KF, Clark MP, Dweik RA, Fitzpatrick AM, Gaston B, Hew M, Hussain I, Jarjour NN, Israel E, Levy BD, Murphy JR, Peters SP, Teague WG, Meyers DA, Busse WW, Wenzel SE; National Heart, Lung, Blood Institute's Severe Asthma Research Program. Moore WC, et al. Among authors: wenzel se. J Allergy Clin Immunol. 2007 Feb;119(2):405-13. doi: 10.1016/j.jaci.2006.11.639. J Allergy Clin Immunol. 2007. PMID: 17291857 Free PMC article.
Severe asthma in adults: what are the important questions?
Chanez P, Wenzel SE, Anderson GP, Anto JM, Bel EH, Boulet LP, Brightling CE, Busse WW, Castro M, Dahlen B, Dahlen SE, Fabbri LM, Holgate ST, Humbert M, Gaga M, Joos GF, Levy B, Rabe KF, Sterk PJ, Wilson SJ, Vachier I. Chanez P, et al. Among authors: wenzel se. J Allergy Clin Immunol. 2007 Jun;119(6):1337-48. doi: 10.1016/j.jaci.2006.11.702. Epub 2007 Apr 9. J Allergy Clin Immunol. 2007. PMID: 17416409
Lung function in adults with stable but severe asthma: air trapping and incomplete reversal of obstruction with bronchodilation.
Sorkness RL, Bleecker ER, Busse WW, Calhoun WJ, Castro M, Chung KF, Curran-Everett D, Erzurum SC, Gaston BM, Israel E, Jarjour NN, Moore WC, Peters SP, Teague WG, Wenzel SE; National Heart, Lung, and Blood Institute Severe Asthma Research Program. Sorkness RL, et al. Among authors: wenzel se. J Appl Physiol (1985). 2008 Feb;104(2):394-403. doi: 10.1152/japplphysiol.00329.2007. Epub 2007 Nov 8. J Appl Physiol (1985). 2008. PMID: 17991792 Free article. Clinical Trial.
Airway lipoxin A4 generation and lipoxin A4 receptor expression are decreased in severe asthma.
Planagumà A, Kazani S, Marigowda G, Haworth O, Mariani TJ, Israel E, Bleecker ER, Curran-Everett D, Erzurum SC, Calhoun WJ, Castro M, Chung KF, Gaston B, Jarjour NN, Busse WW, Wenzel SE, Levy BD. Planagumà A, et al. Among authors: wenzel se. Am J Respir Crit Care Med. 2008 Sep 15;178(6):574-82. doi: 10.1164/rccm.200801-061OC. Epub 2008 Jun 26. Am J Respir Crit Care Med. 2008. PMID: 18583575 Free PMC article.
A randomized, double-blind, placebo-controlled study of tumor necrosis factor-alpha blockade in severe persistent asthma.
Wenzel SE, Barnes PJ, Bleecker ER, Bousquet J, Busse W, Dahlén SE, Holgate ST, Meyers DA, Rabe KF, Antczak A, Baker J, Horvath I, Mark Z, Bernstein D, Kerwin E, Schlenker-Herceg R, Lo KH, Watt R, Barnathan ES, Chanez P; T03 Asthma Investigators. Wenzel SE, et al. Am J Respir Crit Care Med. 2009 Apr 1;179(7):549-58. doi: 10.1164/rccm.200809-1512OC. Epub 2009 Jan 8. Am J Respir Crit Care Med. 2009. PMID: 19136369 Clinical Trial.
An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice.
Reddel HK, Taylor DR, Bateman ED, Boulet LP, Boushey HA, Busse WW, Casale TB, Chanez P, Enright PL, Gibson PG, de Jongste JC, Kerstjens HA, Lazarus SC, Levy ML, O'Byrne PM, Partridge MR, Pavord ID, Sears MR, Sterk PJ, Stoloff SW, Sullivan SD, Szefler SJ, Thomas MD, Wenzel SE; American Thoracic Society/European Respiratory Society Task Force on Asthma Control and Exacerbations. Reddel HK, et al. Among authors: wenzel se. Am J Respir Crit Care Med. 2009 Jul 1;180(1):59-99. doi: 10.1164/rccm.200801-060ST. Am J Respir Crit Care Med. 2009. PMID: 19535666
Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program.
Moore WC, Meyers DA, Wenzel SE, Teague WG, Li H, Li X, D'Agostino R Jr, Castro M, Curran-Everett D, Fitzpatrick AM, Gaston B, Jarjour NN, Sorkness R, Calhoun WJ, Chung KF, Comhair SA, Dweik RA, Israel E, Peters SP, Busse WW, Erzurum SC, Bleecker ER; National Heart, Lung, and Blood Institute's Severe Asthma Research Program. Moore WC, et al. Among authors: wenzel se. Am J Respir Crit Care Med. 2010 Feb 15;181(4):315-23. doi: 10.1164/rccm.200906-0896OC. Epub 2009 Nov 5. Am J Respir Crit Care Med. 2010. PMID: 19892860 Free PMC article.
368 results