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Development of Thioaryl-Based Matrix Metalloproteinase-12 Inhibitors with Alternative Zinc-Binding Groups: Synthesis, Potentiometric, NMR, and Crystallographic Studies.
Nuti E, Cuffaro D, Bernardini E, Camodeca C, Panelli L, Chaves S, Ciccone L, Tepshi L, Vera L, Orlandini E, Nencetti S, Stura EA, Santos MA, Dive V, Rossello A. Nuti E, et al. Among authors: cuffaro d. J Med Chem. 2018 May 24;61(10):4421-4435. doi: 10.1021/acs.jmedchem.8b00096. Epub 2018 May 16. J Med Chem. 2018. PMID: 29727184
Sugar-Based Arylsulfonamide Carboxylates as Selective and Water-Soluble Matrix Metalloproteinase-12 Inhibitors.
Nuti E, Cuffaro D, D'Andrea F, Rosalia L, Tepshi L, Fabbi M, Carbotti G, Ferrini S, Santamaria S, Camodeca C, Ciccone L, Orlandini E, Nencetti S, Stura EA, Dive V, Rossello A. Nuti E, et al. Among authors: cuffaro d, d andrea f. ChemMedChem. 2016 Aug 5;11(15):1626-37. doi: 10.1002/cmdc.201600235. Epub 2016 Jun 30. ChemMedChem. 2016. PMID: 27356908
Bifunctional Inhibitors as a New Tool To Reduce Cancer Cell Invasion by Impairing MMP-9 Homodimerization.
Nuti E, Rosalia L, Cuffaro D, Camodeca C, Giacomelli C, Da Pozzo E, Tuccinardi T, Costa B, Antoni C, Vera L, Ciccone L, Orlandini E, Nencetti S, Dive V, Martini C, Stura EA, Rossello A. Nuti E, et al. Among authors: cuffaro d. ACS Med Chem Lett. 2017 Feb 7;8(3):293-298. doi: 10.1021/acsmedchemlett.6b00446. eCollection 2017 Mar 9. ACS Med Chem Lett. 2017. PMID: 28337319 Free PMC article.
ADAM Metalloproteinases as Potential Drug Targets.
Camodeca C, Cuffaro D, Nuti E, Rossello A. Camodeca C, et al. Among authors: cuffaro d. Curr Med Chem. 2019;26(15):2661-2689. doi: 10.2174/0929867325666180326164104. Curr Med Chem. 2019. PMID: 29589526 Review.
Design and Synthesis of Ionic Liquid-Based Matrix Metalloproteinase Inhibitors (MMPIs): A Simple Approach to Increase Hydrophilicity and to Develop MMPI-Coated Gold Nanoparticles.
D'Andrea F, Nuti E, Becherini S, Cuffaro D, Husanu E, Camodeca C, De Vita E, Zocchi MR, Poggi A, D'Arrigo C, Cappello V, Gemmi M, Nencetti S, Chiappe C, Rossello A. D'Andrea F, et al. Among authors: cuffaro d, d arrigo c. ChemMedChem. 2019 Mar 22;14(6):686-698. doi: 10.1002/cmdc.201800733. Epub 2019 Feb 14. ChemMedChem. 2019. PMID: 30600908
The metalloproteinase ADAM10 requires its activity to sustain surface expression.
Seifert A, Düsterhöft S, Wozniak J, Koo CZ, Tomlinson MG, Nuti E, Rossello A, Cuffaro D, Yildiz D, Ludwig A. Seifert A, et al. Among authors: cuffaro d. Cell Mol Life Sci. 2021 Jan;78(2):715-732. doi: 10.1007/s00018-020-03507-w. Epub 2020 May 5. Cell Mol Life Sci. 2021. PMID: 32372373 Free PMC article.
38 results