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Development of Thioaryl-Based Matrix Metalloproteinase-12 Inhibitors with Alternative Zinc-Binding Groups: Synthesis, Potentiometric, NMR, and Crystallographic Studies.
Nuti E, Cuffaro D, Bernardini E, Camodeca C, Panelli L, Chaves S, Ciccone L, Tepshi L, Vera L, Orlandini E, Nencetti S, Stura EA, Santos MA, Dive V, Rossello A. Nuti E, et al. J Med Chem. 2018 May 24;61(10):4421-4435. doi: 10.1021/acs.jmedchem.8b00096. Epub 2018 May 16. J Med Chem. 2018. PMID: 29727184
Amber force field implementation, molecular modelling study, synthesis and MMP-1/MMP-2 inhibition profile of (R)- and (S)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamides.
Tuccinardi T, Martinelli A, Nuti E, Carelli P, Balzano F, Uccello-Barretta G, Murphy G, Rossello A. Tuccinardi T, et al. Among authors: nuti e. Bioorg Med Chem. 2006 Jun 15;14(12):4260-76. doi: 10.1016/j.bmc.2006.01.056. Epub 2006 Feb 17. Bioorg Med Chem. 2006. PMID: 16483784
96 results