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Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging.
Robinson AR, Yousefzadeh MJ, Rozgaja TA, Wang J, Li X, Tilstra JS, Feldman CH, Gregg SQ, Johnson CH, Skoda EM, Frantz MC, Bell-Temin H, Pope-Varsalona H, Gurkar AU, Nasto LA, Robinson RAS, Fuhrmann-Stroissnigg H, Czerwinska J, McGowan SJ, Cantu-Medellin N, Harris JB, Maniar S, Ross MA, Trussoni CE, LaRusso NF, Cifuentes-Pagano E, Pagano PJ, Tudek B, Vo NV, Rigatti LH, Opresko PL, Stolz DB, Watkins SC, Burd CE, Croix CMS, Siuzdak G, Yates NA, Robbins PD, Wang Y, Wipf P, Kelley EE, Niedernhofer LJ. Robinson AR, et al. Among authors: frantz mc. Redox Biol. 2018 Jul;17:259-273. doi: 10.1016/j.redox.2018.04.007. Epub 2018 Apr 13. Redox Biol. 2018. PMID: 29747066 Free PMC article.
Mitochondria as a target in treatment.
Frantz MC, Wipf P. Frantz MC, et al. Environ Mol Mutagen. 2010 Jun;51(5):462-75. doi: 10.1002/em.20554. Environ Mol Mutagen. 2010. PMID: 20175113 Free PMC article. Review.
Two strategies for the development of mitochondrion-targeted small molecule radiation damage mitigators.
Rwigema JC, Beck B, Wang W, Doemling A, Epperly MW, Shields D, Goff JP, Franicola D, Dixon T, Frantz MC, Wipf P, Tyurina Y, Kagan VE, Wang H, Greenberger JS. Rwigema JC, et al. Among authors: frantz mc. Int J Radiat Oncol Biol Phys. 2011 Jul 1;80(3):860-8. doi: 10.1016/j.ijrobp.2011.01.059. Epub 2011 Apr 13. Int J Radiat Oncol Biol Phys. 2011. PMID: 21493014 Free PMC article.
Design, Synthesis, and Biological Evaluation of PKD Inhibitors.
George KM, Frantz MC, Bravo-Altamirano K, Lavalle CR, Tandon M, Leimgruber S, Sharlow ER, Lazo JS, Wang QJ, Wipf P. George KM, et al. Among authors: frantz mc. Pharmaceutics. 2011;3(2):186-228. doi: 10.3390/pharmaceutics3020186. Pharmaceutics. 2011. PMID: 22267986 Free PMC article.
GS-nitroxide (JP4-039)-mediated radioprotection of human Fanconi anemia cell lines.
Bernard ME, Kim H, Berhane H, Epperly MW, Franicola D, Zhang X, Houghton F, Shields D, Wang H, Bakkenist CJ, Frantz MC, Forbeck EM, Goff JP, Wipf P, Greenberger JS. Bernard ME, et al. Among authors: frantz mc. Radiat Res. 2011 Nov;176(5):603-12. doi: 10.1667/rr2624.1. Epub 2011 Sep 22. Radiat Res. 2011. PMID: 21939290 Free PMC article.
23 results