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Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging.
Robinson AR, Yousefzadeh MJ, Rozgaja TA, Wang J, Li X, Tilstra JS, Feldman CH, Gregg SQ, Johnson CH, Skoda EM, Frantz MC, Bell-Temin H, Pope-Varsalona H, Gurkar AU, Nasto LA, Robinson RAS, Fuhrmann-Stroissnigg H, Czerwinska J, McGowan SJ, Cantu-Medellin N, Harris JB, Maniar S, Ross MA, Trussoni CE, LaRusso NF, Cifuentes-Pagano E, Pagano PJ, Tudek B, Vo NV, Rigatti LH, Opresko PL, Stolz DB, Watkins SC, Burd CE, Croix CMS, Siuzdak G, Yates NA, Robbins PD, Wang Y, Wipf P, Kelley EE, Niedernhofer LJ. Robinson AR, et al. Among authors: yates na. Redox Biol. 2018 Jul;17:259-273. doi: 10.1016/j.redox.2018.04.007. Epub 2018 Apr 13. Redox Biol. 2018. PMID: 29747066 Free PMC article.
Measuring biological age in mice using differential mass spectrometry.
Bell-Temin H, Yousefzadeh MJ, Bondarenko A, Quarles E, Jones-Laughner J, Robbins PD, Ladiges W, Niedernhofer LJ, Yates NA. Bell-Temin H, et al. Among authors: yates na. Aging (Albany NY). 2019 Feb 11;11(3):1045-1061. doi: 10.18632/aging.101810. Aging (Albany NY). 2019. PMID: 30745468 Free PMC article.
Growth arrest by the antitumor steroidal lactone withaferin A in human breast cancer cells is associated with down-regulation and covalent binding at cysteine 303 of β-tubulin.
Antony ML, Lee J, Hahm ER, Kim SH, Marcus AI, Kumari V, Ji X, Yang Z, Vowell CL, Wipf P, Uechi GT, Yates NA, Romero G, Sarkar SN, Singh SV. Antony ML, et al. Among authors: yates na. J Biol Chem. 2014 Jan 17;289(3):1852-65. doi: 10.1074/jbc.M113.496844. Epub 2013 Dec 2. J Biol Chem. 2014. PMID: 24297176 Free PMC article.
Abnormal lipid processing but normal long-term repopulation potential of myc-/- hepatocytes.
Edmunds LR, Otero PA, Sharma L, D'Souza S, Dolezal JM, David S, Lu J, Lamm L, Basantani M, Zhang P, Sipula IJ, Li L, Zeng X, Ding Y, Ding F, Beck ME, Vockley J, Monga SP, Kershaw EE, O'Doherty RM, Kratz LE, Yates NA, Goetzman EP, Scott D, Duncan AW, Prochownik EV. Edmunds LR, et al. Among authors: yates na. Oncotarget. 2016 May 24;7(21):30379-95. doi: 10.18632/oncotarget.8856. Oncotarget. 2016. PMID: 27105497 Free PMC article.
NAD+ bioavailability mediates PARG inhibition-induced replication arrest, intra S-phase checkpoint and apoptosis in glioma stem cells.
Li J, M Saville K, Ibrahim M, Zeng X, McClellan S, Angajala A, Beiser A, Andrews JF, Sun M, Koczor CA, Clark J, Hayat F, Makarov MV, Wilk A, Yates NA, Migaud ME, Sobol RW. Li J, et al. Among authors: yates na. NAR Cancer. 2021 Nov 17;3(4):zcab044. doi: 10.1093/narcan/zcab044. eCollection 2021 Dec. NAR Cancer. 2021. PMID: 34806016 Free PMC article.
Application of an end-to-end biomarker discovery platform to identify target engagement markers in cerebrospinal fluid by high resolution differential mass spectrometry.
Paweletz CP, Wiener MC, Bondarenko AY, Yates NA, Song Q, Liaw A, Lee AY, Hunt BT, Henle ES, Meng F, Sleph HF, Holahan M, Sankaranarayanan S, Simon AJ, Settlage RE, Sachs JR, Shearman M, Sachs AB, Cook JJ, Hendrickson RC. Paweletz CP, et al. Among authors: yates na. J Proteome Res. 2010 Mar 5;9(3):1392-401. doi: 10.1021/pr900925d. J Proteome Res. 2010. PMID: 20095649
75 results