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Bhlhe40 is an essential repressor of IL-10 during Mycobacterium tuberculosis infection.
Huynh JP, Lin CC, Kimmey JM, Jarjour NN, Schwarzkopf EA, Bradstreet TR, Shchukina I, Shpynov O, Weaver CT, Taneja R, Artyomov MN, Edelson BT, Stallings CL. Huynh JP, et al. Among authors: shchukina i. J Exp Med. 2018 Jul 2;215(7):1823-1838. doi: 10.1084/jem.20171704. Epub 2018 May 17. J Exp Med. 2018. PMID: 29773644 Free PMC article.
Bhlhe40 mediates tissue-specific control of macrophage proliferation in homeostasis and type 2 immunity.
Jarjour NN, Schwarzkopf EA, Bradstreet TR, Shchukina I, Lin CC, Huang SC, Lai CW, Cook ME, Taneja R, Stappenbeck TS, Randolph GJ, Artyomov MN, Urban JF Jr, Edelson BT. Jarjour NN, et al. Among authors: shchukina i. Nat Immunol. 2019 Jun;20(6):687-700. doi: 10.1038/s41590-019-0382-5. Epub 2019 May 6. Nat Immunol. 2019. PMID: 31061528 Free PMC article.
Comprehensive Profiling of an Aging Immune System Reveals Clonal GZMK+ CD8+ T Cells as Conserved Hallmark of Inflammaging.
Mogilenko DA, Shpynov O, Andhey PS, Arthur L, Swain A, Esaulova E, Brioschi S, Shchukina I, Kerndl M, Bambouskova M, Yao Z, Laha A, Zaitsev K, Burdess S, Gillfilan S, Stewart SA, Colonna M, Artyomov MN. Mogilenko DA, et al. Among authors: shchukina i. Immunity. 2021 Jan 12;54(1):99-115.e12. doi: 10.1016/j.immuni.2020.11.005. Epub 2020 Dec 2. Immunity. 2021. PMID: 33271118 Free article.
Heterogeneity of meningeal B cells reveals a lymphopoietic niche at the CNS borders.
Brioschi S, Wang WL, Peng V, Wang M, Shchukina I, Greenberg ZJ, Bando JK, Jaeger N, Czepielewski RS, Swain A, Mogilenko DA, Beatty WL, Bayguinov P, Fitzpatrick JAJ, Schuettpelz LG, Fronick CC, Smirnov I, Kipnis J, Shapiro VS, Wu GF, Gilfillan S, Cella M, Artyomov MN, Kleinstein SH, Colonna M. Brioschi S, et al. Among authors: shchukina i. Science. 2021 Jul 23;373(6553):eabf9277. doi: 10.1126/science.abf9277. Epub 2021 Jun 3. Science. 2021. PMID: 34083450 Free PMC article.
IL-33 causes thermogenic failure in aging by expanding dysfunctional adipose ILC2.
Goldberg EL, Shchukina I, Youm YH, Ryu S, Tsusaka T, Young KC, Camell CD, Dlugos T, Artyomov MN, Dixit VD. Goldberg EL, et al. Among authors: shchukina i. Cell Metab. 2021 Nov 2;33(11):2277-2287.e5. doi: 10.1016/j.cmet.2021.08.004. Epub 2021 Sep 1. Cell Metab. 2021. PMID: 34473956 Free PMC article.
Enhanced epigenetic profiling of classical human monocytes reveals a specific signature of healthy aging in the DNA methylome.
Shchukina I, Bagaitkar J, Shpynov O, Loginicheva E, Porter S, Mogilenko DA, Wolin E, Collins P, Demidov G, Artomov M, Zaitsev K, Sidorov S, Camell C, Bambouskova M, Arthur L, Swain A, Panteleeva A, Dievskii A, Kurbatsky E, Tsurinov P, Chernyatchik R, Dixit VD, Jovanovic M, Stewart SA, Daly MJ, Dmitriev S, Oltz EM, Artyomov MN. Shchukina I, et al. Nat Aging. 2021 Jan;1(1):124-141. doi: 10.1038/s43587-020-00002-6. Epub 2020 Nov 23. Nat Aging. 2021. PMID: 34796338 Free PMC article.
Immune ageing at single-cell resolution.
Mogilenko DA, Shchukina I, Artyomov MN. Mogilenko DA, et al. Among authors: shchukina i. Nat Rev Immunol. 2022 Aug;22(8):484-498. doi: 10.1038/s41577-021-00646-4. Epub 2021 Nov 23. Nat Rev Immunol. 2022. PMID: 34815556 Free PMC article. Review.
Single-cell transcriptomics reveals cell-type-specific diversification in human heart failure.
Koenig AL, Shchukina I, Amrute J, Andhey PS, Zaitsev K, Lai L, Bajpai G, Bredemeyer A, Smith G, Jones C, Terrebonne E, Rentschler SL, Artyomov MN, Lavine KJ. Koenig AL, et al. Among authors: shchukina i. Nat Cardiovasc Res. 2022 Mar;1(3):263-280. doi: 10.1038/s44161-022-00028-6. Epub 2022 Mar 16. Nat Cardiovasc Res. 2022. PMID: 35959412 Free PMC article.
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