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Single chain variable fragment against nicastrin inhibits the gamma-secretase activity.
Hayashi I, Takatori S, Urano Y, Iwanari H, Isoo N, Osawa S, Fukuda MA, Kodama T, Hamakubo T, Li T, Wong PC, Tomita T, Iwatsubo T. Hayashi I, et al. Among authors: takatori s. J Biol Chem. 2009 Oct 9;284(41):27838-27847. doi: 10.1074/jbc.M109.055061. Epub 2009 Aug 14. J Biol Chem. 2009. PMID: 19684016 Free PMC article.
Neutralization of the γ-secretase activity by monoclonal antibody against extracellular domain of nicastrin.
Hayashi I, Takatori S, Urano Y, Miyake Y, Takagi J, Sakata-Yanagimoto M, Iwanari H, Osawa S, Morohashi Y, Li T, Wong PC, Chiba S, Kodama T, Hamakubo T, Tomita T, Iwatsubo T. Hayashi I, et al. Among authors: takatori s. Oncogene. 2012 Feb 9;31(6):787-798. doi: 10.1038/onc.2011.265. Epub 2011 Jul 4. Oncogene. 2012. PMID: 21725355 Free PMC article.
Dietary cis-9, trans-11-conjugated linoleic acid reduces amyloid β-protein accumulation and upregulates anti-inflammatory cytokines in an Alzheimer's disease mouse model.
Fujita Y, Kano K, Kishino S, Nagao T, Shen X, Sato C, Hatakeyama H, Ota Y, Niibori S, Nomura A, Kikuchi K, Yasuno W, Takatori S, Kikuchi K, Sano Y, Tomita T, Suzuki T, Aoki J, Zou K, Natori S, Komano H. Fujita Y, et al. Among authors: takatori s. Sci Rep. 2021 May 12;11(1):9749. doi: 10.1038/s41598-021-88870-9. Sci Rep. 2021. PMID: 33980877 Free PMC article.
181 results