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Page 1
(Epi)genetic Inheritance in Schistosoma mansoni: A Systems Approach.
Cosseau C, Wolkenhauer O, Padalino G, Geyer KK, Hoffmann KF, Grunau C. Cosseau C, et al. Among authors: padalino g. Trends Parasitol. 2017 Apr;33(4):285-294. doi: 10.1016/j.pt.2016.12.002. Epub 2016 Dec 28. Trends Parasitol. 2017. PMID: 28040375 Free PMC article. Review.
Erratum to 'Combining bioinformatics, cheminformatics, functional genomics and whole organism approaches for identifying epigenetic drug targets in Schistosoma mansoni' [IJP Drugs Drug Resist. 8 (2018) 559-570].
Padalino G, Ferla S, Brancale A, Chalmers IW, Hoffmann KF. Padalino G, et al. Int J Parasitol Drugs Drug Resist. 2019 Aug;10:91. doi: 10.1016/j.ijpddr.2019.07.001. Epub 2019 Jul 2. Int J Parasitol Drugs Drug Resist. 2019. PMID: 31299537 Free PMC article. No abstract available.
The repositioning of epigenetic probes/inhibitors identifies new anti-schistosomal lead compounds and chemotherapeutic targets.
Whatley KCL, Padalino G, Whiteland H, Geyer KK, Hulme BJ, Chalmers IW, Forde-Thomas J, Ferla S, Brancale A, Hoffmann KF. Whatley KCL, et al. Among authors: padalino g. PLoS Negl Trop Dis. 2019 Nov 15;13(11):e0007693. doi: 10.1371/journal.pntd.0007693. eCollection 2019 Nov. PLoS Negl Trop Dis. 2019. PMID: 31730617 Free PMC article.
Anti-schistosomal activities of quinoxaline-containing compounds: From hit identification to lead optimisation.
Padalino G, El-Sakkary N, Liu LJ, Liu C, Harte DSG, Barnes RE, Sayers E, Forde-Thomas J, Whiteland H, Bassetto M, Ferla S, Johnson G, Jones AT, Caffrey CR, Chalmers I, Brancale A, Hoffmann KF. Padalino G, et al. Eur J Med Chem. 2021 Dec 15;226:113823. doi: 10.1016/j.ejmech.2021.113823. Epub 2021 Sep 10. Eur J Med Chem. 2021. PMID: 34536671 Free PMC article.
Schistosoma mansoni Larval Extracellular Vesicle protein 1 (SmLEV1) is an immunogenic antigen found in EVs released from pre-acetabular glands of invading cercariae.
Gasan TA, Kuipers ME, Roberts GH, Padalino G, Forde-Thomas JE, Wilson S, Wawrzyniak J, Tukahebwa EM, Hoffmann KF, Chalmers IW. Gasan TA, et al. Among authors: padalino g. PLoS Negl Trop Dis. 2021 Nov 18;15(11):e0009981. doi: 10.1371/journal.pntd.0009981. eCollection 2021 Nov. PLoS Negl Trop Dis. 2021. PMID: 34793443 Free PMC article.
Schistosoma mansoni α-N-acetylgalactosaminidase (SmNAGAL) regulates coordinated parasite movement and egg production.
Hulme BJ, Geyer KK, Forde-Thomas JE, Padalino G, Phillips DW, Ittiprasert W, Karinshak SE, Mann VH, Chalmers IW, Brindley PJ, Hokke CH, Hoffmann KF. Hulme BJ, et al. Among authors: padalino g. PLoS Pathog. 2022 Jan 13;18(1):e1009828. doi: 10.1371/journal.ppat.1009828. eCollection 2022 Jan. PLoS Pathog. 2022. PMID: 35025955 Free PMC article.
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