Ho AL - Search Results

1

Impact of race on dose selection of molecular-targeted agents in early-phase oncology trials.

Yokota T, Bendell J, LoRusso P, Tsushima T, Desai V, Kenmotsu H, Watanabe J, Ono A, Murugesan B, Silva J, Naito T, Greenberg J, Kumar P, Wang Y, Jikoh T, Shiga R, Hyman DM, Ho AL, Spriggs DR, Schwartz GK, Gounder MM. Yokota T, et al. Among authors: ho al. Br J Cancer. 2018 Jun;118(12):1571-1579. doi: 10.1038/s41416-018-0102-1. Epub 2018 May 24. Br J Cancer. 2018. PMID: 29795308 Free PMC article. Clinical Trial.

2

Aurora B kinase regulates the postmitotic endoreduplication checkpoint via phosphorylation of the retinoblastoma protein at serine 780.

Nair JS, Ho AL, Tse AN, Coward J, Cheema H, Ambrosini G, Keen N, Schwartz GK. Nair JS, et al. Among authors: ho al. Mol Biol Cell. 2009 Apr;20(8):2218-28. doi: 10.1091/mbc.e08-08-0885. Epub 2009 Feb 18. Mol Biol Cell. 2009. PMID: 19225156 Free PMC article.

3

Targeting of insulin-like growth factor type 1 receptor in Ewing sarcoma: unfulfilled promise or a promising beginning?

Ho AL, Schwartz GK. Ho AL, et al. J Clin Oncol. 2011 Dec 1;29(34):4581-3. doi: 10.1200/JCO.2011.38.2374. Epub 2011 Oct 24. J Clin Oncol. 2011. PMID: 22025158 Free PMC article. No abstract available.

4

The induction of polyploidy or apoptosis by the Aurora A kinase inhibitor MK8745 is p53-dependent.

Nair JS, Ho AL, Schwartz GK. Nair JS, et al. Among authors: ho al. Cell Cycle. 2012 Feb 15;11(4):807-17. doi: 10.4161/cc.11.4.19323. Epub 2012 Feb 15. Cell Cycle. 2012. PMID: 22293494 Free PMC article.

5

PDGF receptor alpha is an alternative mediator of rapamycin-induced Akt activation: implications for combination targeted therapy of synovial sarcoma.

Ho AL, Vasudeva SD, Laé M, Saito T, Barbashina V, Antonescu CR, Ladanyi M, Schwartz GK. Ho AL, et al. Cancer Res. 2012 Sep 1;72(17):4515-25. doi: 10.1158/0008-5472.CAN-12-1319. Epub 2012 Jul 10. Cancer Res. 2012. PMID: 22787122 Free PMC article.

6

Impact of combined mTOR and MEK inhibition in uveal melanoma is driven by tumor genotype.

Ho AL, Musi E, Ambrosini G, Nair JS, Deraje Vasudeva S, de Stanchina E, Schwartz GK. Ho AL, et al. PLoS One. 2012;7(7):e40439. doi: 10.1371/journal.pone.0040439. Epub 2012 Jul 10. PLoS One. 2012. PMID: 22808163 Free PMC article.

7

A phase 1 study of everolimus plus docetaxel plus cisplatin as induction chemotherapy for patients with locally and/or regionally advanced head and neck cancer.

Fury MG, Sherman E, Ho AL, Xiao H, Tsai F, Nwankwo O, Sima C, Heguy A, Katabi N, Haque S, Pfister DG. Fury MG, et al. Among authors: ho al. Cancer. 2013 May 15;119(10):1823-31. doi: 10.1002/cncr.27986. Epub 2013 Feb 13. Cancer. 2013. PMID: 23408298 Free PMC article. Clinical Trial.

8

Inhibition of mutant GNAQ signaling in uveal melanoma induces AMPK-dependent autophagic cell death.

Ambrosini G, Musi E, Ho AL, de Stanchina E, Schwartz GK. Ambrosini G, et al. Among authors: ho al. Mol Cancer Ther. 2013 May;12(5):768-76. doi: 10.1158/1535-7163.MCT-12-1020. Epub 2013 Feb 26. Mol Cancer Ther. 2013. PMID: 23443802

9

Cixutumumab and temsirolimus for patients with bone and soft-tissue sarcoma: a multicentre, open-label, phase 2 trial.

Schwartz GK, Tap WD, Qin LX, Livingston MB, Undevia SD, Chmielowski B, Agulnik M, Schuetze SM, Reed DR, Okuno SH, Ludwig JA, Keedy V, Rietschel P, Kraft AS, Adkins D, Van Tine BA, Brockstein B, Yim V, Bitas C, Abdullah A, Antonescu CR, Condy M, Dickson MA, Vasudeva SD, Ho AL, Doyle LA, Chen HX, Maki RG. Schwartz GK, et al. Among authors: ho al. Lancet Oncol. 2013 Apr;14(4):371-82. doi: 10.1016/S1470-2045(13)70049-4. Epub 2013 Mar 8. Lancet Oncol. 2013. PMID: 23477833 Free PMC article. Clinical Trial.

10

PTEN regulates sensitivity of melanoma cells to RO4929097, the γ-secretase inhibitor.

Nair JS, Sheikh T, Ho AL, Schwartz GK. Nair JS, et al. Among authors: ho al. Anticancer Res. 2013 Apr;33(4):1307-16. Anticancer Res. 2013. PMID: 23564767

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