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Page 1
Genome-wide association study of response to methotrexate in early rheumatoid arthritis patients.
Taylor JC, Bongartz T, Massey J, Mifsud B, Spiliopoulou A, Scott IC, Wang J, Morgan M, Plant D, Colombo M, Orchard P, Twigg S, McInnes IB, Porter D, Freeston JE, Nam JL, Cordell HJ, Isaacs JD, Strathdee JL, Arnett D, de Hair MJH, Tak PP, Aslibekyan S, van Vollenhoven RF, Padyukov L, Bridges SL, Pitzalis C, Cope AP, Verstappen SMM, Emery P, Barnes MR, Agakov F, McKeigue P, Mushiroda T, Kubo M, Weinshilboum R, Barton A, Morgan AW, Barrett JH; MATURA; and PAMERA; Consortia. Taylor JC, et al. Among authors: weinshilboum r. Pharmacogenomics J. 2018 Jul;18(4):528-538. doi: 10.1038/s41397-018-0025-5. Epub 2018 May 25. Pharmacogenomics J. 2018. PMID: 29795407 Free article. Review.
A polygenic risk score for breast cancer in women receiving tamoxifen or raloxifene on NSABP P-1 and P-2.
Vachon CM, Schaid DJ, Ingle JN, Wickerham DL, Kubo M, Mushiroda T, Goetz MP, Carlson EE, Paik S, Wolmark N, Nakamura Y, Wang L, Weinshilboum R, Couch FJ. Vachon CM, et al. Among authors: weinshilboum r. Breast Cancer Res Treat. 2015 Jan;149(2):517-23. doi: 10.1007/s10549-014-3175-4. Epub 2015 Jan 10. Breast Cancer Res Treat. 2015. PMID: 25575444 Free PMC article.
The International SSRI Pharmacogenomics Consortium (ISPC): a genome-wide association study of antidepressant treatment response.
Biernacka JM, Sangkuhl K, Jenkins G, Whaley RM, Barman P, Batzler A, Altman RB, Arolt V, Brockmöller J, Chen CH, Domschke K, Hall-Flavin DK, Hong CJ, Illi A, Ji Y, Kampman O, Kinoshita T, Leinonen E, Liou YJ, Mushiroda T, Nonen S, Skime MK, Wang L, Baune BT, Kato M, Liu YL, Praphanphoj V, Stingl JC, Tsai SJ, Kubo M, Klein TE, Weinshilboum R. Biernacka JM, et al. Among authors: weinshilboum r. Transl Psychiatry. 2015 Apr 21;5(4):e553. doi: 10.1038/tp.2015.47. Transl Psychiatry. 2015. PMID: 25897834 Free PMC article.
Genetic contributions to alcohol use disorder treatment outcomes: a genome-wide pharmacogenomics study.
Biernacka JM, Coombes BJ, Batzler A, Ho AM, Geske JR, Frank J, Hodgkinson C, Skime M, Colby C, Zillich L, Pozsonyiova S, Ho MF, Kiefer F, Rietschel M, Weinshilboum R, O'Malley SS, Mann K, Anton R, Goldman D, Karpyak VM. Biernacka JM, et al. Among authors: weinshilboum r. Neuropsychopharmacology. 2021 Nov;46(12):2132-2139. doi: 10.1038/s41386-021-01097-0. Epub 2021 Jul 23. Neuropsychopharmacology. 2021. PMID: 34302059 Free PMC article.
Clinical predictors of response to methotrexate in patients with rheumatoid arthritis: a machine learning approach using clinical trial data.
Duong SQ, Crowson CS, Athreya A, Atkinson EJ, Davis JM 3rd, Warrington KJ, Matteson EL, Weinshilboum R, Wang L, Myasoedova E. Duong SQ, et al. Among authors: weinshilboum r. Arthritis Res Ther. 2022 Jul 1;24(1):162. doi: 10.1186/s13075-022-02851-5. Arthritis Res Ther. 2022. PMID: 35778714 Free PMC article. Clinical Trial.
Polymorphic variation in TPMT is the principal determinant of TPMT phenotype: A meta-analysis of three genome-wide association studies.
Tamm R, Mägi R, Tremmel R, Winter S, Mihailov E, Smid A, Möricke A, Klein K, Schrappe M, Stanulla M, Houlston R, Weinshilboum R, Mlinarič Raščan I, Metspalu A, Milani L, Schwab M, Schaeffeler E. Tamm R, et al. Among authors: weinshilboum r. Clin Pharmacol Ther. 2017 May;101(5):684-695. doi: 10.1002/cpt.540. Epub 2017 Feb 1. Clin Pharmacol Ther. 2017. PMID: 27770449 Free PMC article. Review.
Polygenic risk scores for major depressive disorder and neuroticism as predictors of antidepressant response: Meta-analysis of three treatment cohorts.
Ward J, Graham N, Strawbridge RJ, Ferguson A, Jenkins G, Chen W, Hodgson K, Frye M, Weinshilboum R, Uher R, Lewis CM, Biernacka J, Smith DJ. Ward J, et al. Among authors: weinshilboum r. PLoS One. 2018 Sep 21;13(9):e0203896. doi: 10.1371/journal.pone.0203896. eCollection 2018. PLoS One. 2018. PMID: 30240446 Free PMC article.
Genome-wide association study for circulating FGF21 in patients with alcohol use disorder: Molecular links between the SNHG16 locus and catecholamine metabolism.
Ho MF, Zhang C, Moon I, Wei L, Coombes B, Biernacka J, Skime M, Choi DS, Frye M, Schmidt K, Gliske K, Braughton J, Ngo Q, Skillon C, Seppala M, Oesterle T, Karpyak V, Li H, Weinshilboum R. Ho MF, et al. Among authors: weinshilboum r. Mol Metab. 2022 Sep;63:101534. doi: 10.1016/j.molmet.2022.101534. Epub 2022 Jun 22. Mol Metab. 2022. PMID: 35752286 Free PMC article.
549 results