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Simvastatin interferes with cancer 'stem-cell' plasticity reducing metastasis in ovarian cancer.
Kato S, Liberona MF, Cerda-Infante J, Sánchez M, Henríquez J, Bizama C, Bravo ML, Gonzalez P, Gejman R, Brañes J, García K, Ibañez C, Owen GI, Roa JC, Montecinos V, Cuello MA. Kato S, et al. Among authors: branes j. Endocr Relat Cancer. 2018 Oct;25(10):821-836. doi: 10.1530/ERC-18-0132. Epub 2018 May 30. Endocr Relat Cancer. 2018. PMID: 29848667
Platelets enhance tissue factor protein and metastasis initiating cell markers, and act as chemoattractants increasing the migration of ovarian cancer cells.
Orellana R, Kato S, Erices R, Bravo ML, Gonzalez P, Oliva B, Cubillos S, Valdivia A, Ibañez C, Brañes J, Barriga MI, Bravo E, Alonso C, Bustamente E, Castellon E, Hidalgo P, Trigo C, Panes O, Pereira J, Mezzano D, Cuello MA, Owen GI. Orellana R, et al. Among authors: branes j. BMC Cancer. 2015 Apr 15;15:290. doi: 10.1186/s12885-015-1304-z. BMC Cancer. 2015. PMID: 25886038 Free PMC article.
Leptin stimulates migration and invasion and maintains cancer stem-like properties in ovarian cancer cells: an explanation for poor outcomes in obese women.
Kato S, Abarzua-Catalan L, Trigo C, Delpiano A, Sanhueza C, García K, Ibañez C, Hormazábal K, Diaz D, Brañes J, Castellón E, Bravo E, Owen G, Cuello MA. Kato S, et al. Among authors: branes j. Oncotarget. 2015 Aug 28;6(25):21100-19. doi: 10.18632/oncotarget.4228. Oncotarget. 2015. PMID: 26053184 Free PMC article.
The oestrogen metabolite 2-methoxyoestradiol alone or in combination with tumour necrosis factor-related apoptosis-inducing ligand mediates apoptosis in cancerous but not healthy cells of the human endometrium.
Kato S, Sadarangani A, Lange S, Villalón M, Brañes J, Brosens JJ, Owen GI, Cuello M. Kato S, et al. Among authors: branes j. Endocr Relat Cancer. 2007 Jun;14(2):351-68. doi: 10.1677/ERC-07-0008. Endocr Relat Cancer. 2007. PMID: 17639050 Free PMC article.
Metformin, at concentrations corresponding to the treatment of diabetes, potentiates the cytotoxic effects of carboplatin in cultures of ovarian cancer cells.
Erices R, Bravo ML, Gonzalez P, Oliva B, Racordon D, Garrido M, Ibañez C, Kato S, Brañes J, Pizarro J, Barriga MI, Barra A, Bravo E, Alonso C, Bustamente E, Cuello MA, Owen GI. Erices R, et al. Among authors: branes j. Reprod Sci. 2013 Dec;20(12):1433-46. doi: 10.1177/1933719113488441. Epub 2013 May 7. Reprod Sci. 2013. PMID: 23653391 Free PMC article.
Diabetic concentrations of metformin inhibit platelet-mediated ovarian cancer cell progression.
Erices R, Cubillos S, Aravena R, Santoro F, Marquez M, Orellana R, Ramírez C, González P, Fuenzalida P, Bravo ML, Oliva B, Kato S, Ibañez C, Brañes J, Bravo E, Alonso C, García K, Arab C, Torres VA, Godoy AS, Pereira J, Bustos G, Cardenas JC, Cuello MA, Owen GI. Erices R, et al. Among authors: branes j. Oncotarget. 2017 Mar 28;8(13):20865-20880. doi: 10.18632/oncotarget.15348. Oncotarget. 2017. PMID: 28209916 Free PMC article.
LEPTIN PROMOTES A MORE AGGRESIVE BEHAVIOR OF OVARIAN CANCER CELLS: A POTENTIAL EXPLANATION FOR A WORSE PROGNOSIS IN OBESE OVARIAN CANCER PATIENTS: IGCS-0095 Ovarian Cancer.
Cuello-Fredes M, Kato S, Abarzúa-Catalán L, Delpiano A, Trigo C, García K, Sanhueza C, Ibañez C, Brañes J, Castellon E, Owen G. Cuello-Fredes M, et al. Among authors: branes j. Int J Gynecol Cancer. 2015 May;25 Suppl 1:67. doi: 10.1097/00009577-201505001-00052. Int J Gynecol Cancer. 2015. PMID: 25955943 No abstract available.
44 results