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Simvastatin interferes with cancer 'stem-cell' plasticity reducing metastasis in ovarian cancer.
Kato S, Liberona MF, Cerda-Infante J, Sánchez M, Henríquez J, Bizama C, Bravo ML, Gonzalez P, Gejman R, Brañes J, García K, Ibañez C, Owen GI, Roa JC, Montecinos V, Cuello MA. Kato S, et al. Among authors: gonzalez p. Endocr Relat Cancer. 2018 Oct;25(10):821-836. doi: 10.1530/ERC-18-0132. Epub 2018 May 30. Endocr Relat Cancer. 2018. PMID: 29848667
Metformin, at concentrations corresponding to the treatment of diabetes, potentiates the cytotoxic effects of carboplatin in cultures of ovarian cancer cells.
Erices R, Bravo ML, Gonzalez P, Oliva B, Racordon D, Garrido M, Ibañez C, Kato S, Brañes J, Pizarro J, Barriga MI, Barra A, Bravo E, Alonso C, Bustamente E, Cuello MA, Owen GI. Erices R, et al. Among authors: gonzalez p. Reprod Sci. 2013 Dec;20(12):1433-46. doi: 10.1177/1933719113488441. Epub 2013 May 7. Reprod Sci. 2013. PMID: 23653391 Free PMC article.
Independent anti-angiogenic capacities of coagulation factors X and Xa.
Lange S, Gonzalez I, Pinto MP, Arce M, Valenzuela R, Aranda E, Elliot M, Alvarez M, Henriquez S, Velasquez EV, Orge F, Oliva B, Gonzalez P, Villalon M, Cautivo KM, Kalergis AM, Pereira K, Mendoza C, Saez C, Kato S, Cuello MA, Parborell F, Irusta G, Palma V, Allende ML, Owen GI. Lange S, et al. Among authors: gonzalez i, gonzalez p. J Cell Physiol. 2014 Nov;229(11):1673-80. doi: 10.1002/jcp.24612. J Cell Physiol. 2014. PMID: 24615682
Platelets enhance tissue factor protein and metastasis initiating cell markers, and act as chemoattractants increasing the migration of ovarian cancer cells.
Orellana R, Kato S, Erices R, Bravo ML, Gonzalez P, Oliva B, Cubillos S, Valdivia A, Ibañez C, Brañes J, Barriga MI, Bravo E, Alonso C, Bustamente E, Castellon E, Hidalgo P, Trigo C, Panes O, Pereira J, Mezzano D, Cuello MA, Owen GI. Orellana R, et al. Among authors: gonzalez p. BMC Cancer. 2015 Apr 15;15:290. doi: 10.1186/s12885-015-1304-z. BMC Cancer. 2015. PMID: 25886038 Free PMC article.
Diabetic concentrations of metformin inhibit platelet-mediated ovarian cancer cell progression.
Erices R, Cubillos S, Aravena R, Santoro F, Marquez M, Orellana R, Ramírez C, González P, Fuenzalida P, Bravo ML, Oliva B, Kato S, Ibañez C, Brañes J, Bravo E, Alonso C, García K, Arab C, Torres VA, Godoy AS, Pereira J, Bustos G, Cardenas JC, Cuello MA, Owen GI. Erices R, et al. Among authors: gonzalez p. Oncotarget. 2017 Mar 28;8(13):20865-20880. doi: 10.18632/oncotarget.15348. Oncotarget. 2017. PMID: 28209916 Free PMC article.
Structural and functional identification of vasculogenic mimicry in vitro.
Racordon D, Valdivia A, Mingo G, Erices R, Aravena R, Santoro F, Bravo ML, Ramirez C, Gonzalez P, Sandoval A, González A, Retamal C, Kogan MJ, Kato S, Cuello MA, Osorio G, Nualart F, Alvares P, Gago-Arias A, Fabri D, Espinoza I, Sanchez B, Corvalán AH, Pinto MP, Owen GI. Racordon D, et al. Among authors: gonzalez a, gonzalez p. Sci Rep. 2017 Aug 1;7(1):6985. doi: 10.1038/s41598-017-07622-w. Sci Rep. 2017. PMID: 28765613 Free PMC article.
Coagulation Factor Xa Promotes Solid Tumor Growth, Experimental Metastasis and Endothelial Cell Activation.
Arce M, Pinto MP, Galleguillos M, Muñoz C, Lange S, Ramirez C, Erices R, Gonzalez P, Velasquez E, Tempio F, Lopez MN, Salazar-Onfray F, Cautivo K, Kalergis AM, Cruz S, Lladser Á, Lobos-González L, Valenzuela G, Olivares N, Sáez C, Koning T, Sánchez FA, Fuenzalida P, Godoy A, Contreras Orellana P, Leyton L, Lugano R, Dimberg A, Quest AFG, Owen GI. Arce M, et al. Among authors: gonzalez p. Cancers (Basel). 2019 Aug 2;11(8):1103. doi: 10.3390/cancers11081103. Cancers (Basel). 2019. PMID: 31382462 Free PMC article.
2,066 results