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Brief Report: Interleukin-17 Blockade With Secukinumab in Peripheral Spondyloarthritis Impacts Synovial Immunopathology Without Compromising Systemic Immune Responses.
van Mens LJJ, van de Sande MGH, Menegatti S, Chen S, Blijdorp ICJ, de Jong HM, Fluri IA, Latuhihin TE, van Kuijk AWR, Rogge L, Yeremenko NG, Baeten DLP. van Mens LJJ, et al. Among authors: menegatti s. Arthritis Rheumatol. 2018 Dec;70(12):1994-2002. doi: 10.1002/art.40581. Epub 2018 Oct 17. Arthritis Rheumatol. 2018. PMID: 29869838 Clinical Trial.
Expansion of Interleukin-22- and Granulocyte-Macrophage Colony-Stimulating Factor-Expressing, but Not Interleukin-17A-Expressing, Group 3 Innate Lymphoid Cells in the Inflamed Joints of Patients With Spondyloarthritis.
Blijdorp ICJ, Menegatti S, van Mens LJJ, van de Sande MGH, Chen S, Hreggvidsdottir HS, Noordenbos T, Latuhihin TE, Bernink JH, Spits H, Rogge L, Baeten DLP, Yeremenko NG. Blijdorp ICJ, et al. Among authors: menegatti s. Arthritis Rheumatol. 2019 Mar;71(3):392-402. doi: 10.1002/art.40736. Epub 2019 Jan 15. Arthritis Rheumatol. 2019. PMID: 30260078 Free PMC article.
Immune response profiling of patients with spondyloarthritis reveals signalling networks mediating TNF-blocker function in vivo.
Menegatti S, Guillemot V, Latis E, Yahia-Cherbal H, Mittermüller D, Rouilly V, Mascia E, Rosine N, Koturan S, Millot GA, Leloup C, Duffy D, Gleizes A, Hacein-Bey-Abina S; Milieu Intérieur Consortium; Sellam J, Berenbaum F, Miceli-Richard C, Dougados M, Bianchi E, Rogge L. Menegatti S, et al. Ann Rheum Dis. 2021 Apr;80(4):475-486. doi: 10.1136/annrheumdis-2020-218304. Epub 2020 Dec 2. Ann Rheum Dis. 2021. PMID: 33268443 Free PMC article.
IL-12 drives functional plasticity of human group 2 innate lymphoid cells.
Lim AI, Menegatti S, Bustamante J, Le Bourhis L, Allez M, Rogge L, Casanova JL, Yssel H, Di Santo JP. Lim AI, et al. Among authors: menegatti s. J Exp Med. 2016 Apr 4;213(4):569-83. doi: 10.1084/jem.20151750. Epub 2016 Mar 14. J Exp Med. 2016. PMID: 26976630 Free PMC article.
In vivo genome-wide CRISPR screens identify SOCS1 as intrinsic checkpoint of CD4+ TH1 cell response.
Sutra Del Galy A, Menegatti S, Fuentealba J, Lucibello F, Perrin L, Helft J, Darbois A, Saitakis M, Tosello J, Rookhuizen D, Deloger M, Gestraud P, Socié G, Amigorena S, Lantz O, Menger L. Sutra Del Galy A, et al. Among authors: menegatti s. Sci Immunol. 2021 Dec 3;6(66):eabe8219. doi: 10.1126/sciimmunol.abe8219. Epub 2021 Dec 3. Sci Immunol. 2021. PMID: 34860579
Methods to edit T cells for cancer immunotherapy.
Lucibello F, Menegatti S, Menger L. Lucibello F, et al. Among authors: menegatti s. Methods Enzymol. 2020;631:107-135. doi: 10.1016/bs.mie.2019.05.048. Epub 2019 Jul 25. Methods Enzymol. 2020. PMID: 31948544 Review.
Ablation of FAS confers allogeneic CD3- CAR T cells with resistance to rejection by T cells and natural killer cells.
Menegatti S, Lopez-Cobo S, Sutra Del Galy A, Fuentealba J, Silva L, Perrin L, Heurtebise-Chrétien S, Pottez-Jouatte V, Darbois A, Burgdorf N, Privat AL, Simon A, Laprie-Sentenac M, Saitakis M, Wick B, Webber BR, Moriarity BS, Lantz O, Amigorena S, Menger L. Menegatti S, et al. Nat Biomed Eng. 2024 Nov 18. doi: 10.1038/s41551-024-01282-8. Online ahead of print. Nat Biomed Eng. 2024. PMID: 39558141
103 results