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Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells.
Hitzel J, Lee E, Zhang Y, Bibli SI, Li X, Zukunft S, Pflüger B, Hu J, Schürmann C, Vasconez AE, Oo JA, Kratzer A, Kumar S, Rezende F, Josipovic I, Thomas D, Giral H, Schreiber Y, Geisslinger G, Fork C, Yang X, Sigala F, Romanoski CE, Kroll J, Jo H, Landmesser U, Lusis AJ, Namgaladze D, Fleming I, Leisegang MS, Zhu J, Brandes RP. Hitzel J, et al. Among authors: geisslinger g. Nat Commun. 2018 Jun 12;9(1):2292. doi: 10.1038/s41467-018-04602-0. Nat Commun. 2018. PMID: 29895827 Free PMC article.
Soluble epoxide hydrolase deficiency attenuates neointima formation in the femoral cuff model of hyperlipidemic mice.
Revermann M, Schloss M, Barbosa-Sicard E, Mieth A, Liebner S, Morisseau C, Geisslinger G, Schermuly RT, Fleming I, Hammock BD, Brandes RP. Revermann M, et al. Among authors: geisslinger g. Arterioscler Thromb Vasc Biol. 2010 May;30(5):909-14. doi: 10.1161/ATVBAHA.110.204099. Epub 2010 Mar 11. Arterioscler Thromb Vasc Biol. 2010. PMID: 20224052 Free PMC article.
Inhibitors of specific ceramide synthases.
Schiffmann S, Hartmann D, Fuchs S, Birod K, Ferreiròs N, Schreiber Y, Zivkovic A, Geisslinger G, Grösch S, Stark H. Schiffmann S, et al. Among authors: geisslinger g. Biochimie. 2012 Feb;94(2):558-65. doi: 10.1016/j.biochi.2011.09.007. Epub 2011 Sep 17. Biochimie. 2012. PMID: 21945810
Soluble epoxide hydrolase limits mechanical hyperalgesia during inflammation.
Brenneis C, Sisignano M, Coste O, Altenrath K, Fischer MJ, Angioni C, Fleming I, Brandes RP, Reeh PW, Woolf CJ, Geisslinger G, Scholich K. Brenneis C, et al. Among authors: geisslinger g. Mol Pain. 2011 Oct 4;7:78. doi: 10.1186/1744-8069-7-78. Mol Pain. 2011. PMID: 21970373 Free PMC article.
608 results