Chen J - Search Results

1

Efficient generation of mouse models of human diseases via ABE- and BE-mediated base editing.

Liu Z, Lu Z, Yang G, Huang S, Li G, Feng S, Liu Y, Li J, Yu W, Zhang Y, Chen J, Sun Q, Huang X. Liu Z, et al. Among authors: chen j. Nat Commun. 2018 Jun 14;9(1):2338. doi: 10.1038/s41467-018-04768-7. Nat Commun. 2018. PMID: 29904106 Free PMC article.

2

Highly efficient and precise base editing in discarded human tripronuclear embryos.

Li G, Liu Y, Zeng Y, Li J, Wang L, Yang G, Chen D, Shang X, Chen J, Huang X, Liu J. Li G, et al. Among authors: chen j, chen d. Protein Cell. 2017 Oct;8(10):776-779. doi: 10.1007/s13238-017-0458-7. Protein Cell. 2017. PMID: 28825190 Free PMC article. No abstract available.

3

APOBEC3 induces mutations during repair of CRISPR-Cas9-generated DNA breaks.

Lei L, Chen H, Xue W, Yang B, Hu B, Wei J, Wang L, Cui Y, Li W, Wang J, Yan L, Shang W, Gao J, Sha J, Zhuang M, Huang X, Shen B, Yang L, Chen J. Lei L, et al. Among authors: chen j, chen h. Nat Struct Mol Biol. 2018 Jan;25(1):45-52. doi: 10.1038/s41594-017-0004-6. Epub 2017 Dec 11. Nat Struct Mol Biol. 2018. PMID: 29323274

4

Base editing with a Cpf1-cytidine deaminase fusion.

Li X, Wang Y, Liu Y, Yang B, Wang X, Wei J, Lu Z, Zhang Y, Wu J, Huang X, Yang L, Chen J. Li X, et al. Among authors: chen j. Nat Biotechnol. 2018 Apr;36(4):324-327. doi: 10.1038/nbt.4102. Epub 2018 Mar 19. Nat Biotechnol. 2018. PMID: 29553573

5

BE-PLUS: a new base editing tool with broadened editing window and enhanced fidelity.

Jiang W, Feng S, Huang S, Yu W, Li G, Yang G, Liu Y, Zhang Y, Zhang L, Hou Y, Chen J, Chen J, Huang X. Jiang W, et al. Among authors: chen j. Cell Res. 2018 Aug;28(8):855-861. doi: 10.1038/s41422-018-0052-4. Epub 2018 Jun 6. Cell Res. 2018. PMID: 29875396 Free PMC article.

6

Efficient base editing in methylated regions with a human APOBEC3A-Cas9 fusion.

Wang X, Li J, Wang Y, Yang B, Wei J, Wu J, Wang R, Huang X, Chen J, Yang L. Wang X, et al. Among authors: chen j. Nat Biotechnol. 2018 Nov;36(10):946-949. doi: 10.1038/nbt.4198. Epub 2018 Aug 20. Nat Biotechnol. 2018. PMID: 30125268

7

Correction of the Marfan Syndrome Pathogenic FBN1 Mutation by Base Editing in Human Cells and Heterozygous Embryos.

Zeng Y, Li J, Li G, Huang S, Yu W, Zhang Y, Chen D, Chen J, Liu J, Huang X. Zeng Y, et al. Among authors: chen j, chen d. Mol Ther. 2018 Nov 7;26(11):2631-2637. doi: 10.1016/j.ymthe.2018.08.007. Epub 2018 Aug 14. Mol Ther. 2018. PMID: 30166242 Free PMC article.

8

Efficient base editing in G/C-rich regions to model androgen insensitivity syndrome.

Li J, Liu Z, Huang S, Wang X, Li G, Xu Y, Yu W, Chen S, Zhang Y, Ma H, Ke Z, Chen J, Sun Q, Huang X. Li J, et al. Among authors: chen j, chen s. Cell Res. 2019 Feb;29(2):174-176. doi: 10.1038/s41422-018-0133-4. Epub 2019 Jan 3. Cell Res. 2019. PMID: 30607018 Free PMC article. No abstract available.

9

Cas12a Base Editors Induce Efficient and Specific Editing with Low DNA Damage Response.

Wang X, Ding C, Yu W, Wang Y, He S, Yang B, Xiong YC, Wei J, Li J, Liang J, Lu Z, Zhu W, Wu J, Zhou Z, Huang X, Liu Z, Yang L, Chen J. Wang X, et al. Among authors: chen j. Cell Rep. 2020 Jun 2;31(9):107723. doi: 10.1016/j.celrep.2020.107723. Cell Rep. 2020. PMID: 32492431 Free article.

10

Eliminating base-editor-induced genome-wide and transcriptome-wide off-target mutations.

Wang L, Xue W, Zhang H, Gao R, Qiu H, Wei J, Zhou L, Lei YN, Wu X, Li X, Liu C, Wu J, Chen Q, Ma H, Huang X, Cai C, Zhang Y, Yang B, Yin H, Yang L, Chen J. Wang L, et al. Among authors: chen j, chen q. Nat Cell Biol. 2021 May;23(5):552-563. doi: 10.1038/s41556-021-00671-4. Epub 2021 May 10. Nat Cell Biol. 2021. PMID: 33972728

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