Xu Q - Search Results

1

Development and validation of an oxygen dissociation assay, a screening platform for discovering, and characterizing hemoglobin-oxygen affinity modifiers.

Patel MP, Siu V, Silva-Garcia A, Xu Q, Li Z, Oksenberg D. Patel MP, et al. Among authors: xu q. Drug Des Devel Ther. 2018 Jun 1;12:1599-1607. doi: 10.2147/DDDT.S157570. eCollection 2018. Drug Des Devel Ther. 2018. PMID: 29910606 Free PMC article.

2

GBT440 increases haemoglobin oxygen affinity, reduces sickling and prolongs RBC half-life in a murine model of sickle cell disease.

Oksenberg D, Dufu K, Patel MP, Chuang C, Li Z, Xu Q, Silva-Garcia A, Zhou C, Hutchaleelaha A, Patskovska L, Patskovsky Y, Almo SC, Sinha U, Metcalf BW, Archer DR. Oksenberg D, et al. Among authors: xu q. Br J Haematol. 2016 Oct;175(1):141-53. doi: 10.1111/bjh.14214. Epub 2016 Jul 5. Br J Haematol. 2016. PMID: 27378309 Free article.

3

Increased hemoglobin-oxygen affinity ameliorates bleomycin-induced hypoxemia and pulmonary fibrosis.

Geng X, Dufu K, Hutchaleelaha A, Xu Q, Li Z, Li CM, Patel MP, Vlahakis N, Lehrer-Graiwer J, Oksenberg D. Geng X, et al. Among authors: xu q. Physiol Rep. 2016 Sep;4(17):e12965. doi: 10.14814/phy2.12965. Physiol Rep. 2016. PMID: 27624688 Free PMC article.

4

Structure-Guided Design of Novel, Potent, and Selective Macrocyclic Plasma Kallikrein Inhibitors.

Li Z, Partridge J, Silva-Garcia A, Rademacher P, Betz A, Xu Q, Sham H, Hu Y, Shan Y, Liu B, Zhang Y, Shi H, Xu Q, Ma X, Zhang L. Li Z, et al. Among authors: xu q. ACS Med Chem Lett. 2016 Dec 6;8(2):185-190. doi: 10.1021/acsmedchemlett.6b00384. eCollection 2017 Feb 9. ACS Med Chem Lett. 2016. PMID: 28197309 Free PMC article.

5

Discovery of GBT440, an Orally Bioavailable R-State Stabilizer of Sickle Cell Hemoglobin.

Metcalf B, Chuang C, Dufu K, Patel MP, Silva-Garcia A, Johnson C, Lu Q, Partridge JR, Patskovska L, Patskovsky Y, Almo SC, Jacobson MP, Hua L, Xu Q, Gwaltney SL 2nd, Yee C, Harris J, Morgan BP, James J, Xu D, Hutchaleelaha A, Paulvannan K, Oksenberg D, Li Z. Metcalf B, et al. Among authors: xu q, xu d. ACS Med Chem Lett. 2017 Jan 23;8(3):321-326. doi: 10.1021/acsmedchemlett.6b00491. eCollection 2017 Mar 9. ACS Med Chem Lett. 2017. PMID: 28337324 Free PMC article.

6

GBT1118, a potent allosteric modifier of hemoglobin O₂ affinity, increases tolerance to severe hypoxia in mice.

Dufu K, Yalcin O, Ao-Ieong ESY, Hutchaleelala A, Xu Q, Li Z, Vlahakis N, Oksenberg D, Lehrer-Graiwer J, Cabrales P. Dufu K, et al. Among authors: xu q. Am J Physiol Heart Circ Physiol. 2017 Aug 1;313(2):H381-H391. doi: 10.1152/ajpheart.00772.2016. Epub 2017 May 19. Am J Physiol Heart Circ Physiol. 2017. PMID: 28526710 Free PMC article.

7

GBT1118, a compound that increases the oxygen affinity of hemoglobin, improves survival in murine hypoxic acute lung injury.

Putz ND, Shaver CM, Dufu K, Li CM, Xu Q, Hutchaleelaha A, Lehrer-Graiwer J, Majka SM, Ware LB, Bastarache JA. Putz ND, et al. Among authors: xu q. J Appl Physiol (1985). 2018 Apr 1;124(4):899-905. doi: 10.1152/japplphysiol.00079.2017. Epub 2017 Dec 14. J Appl Physiol (1985). 2018. PMID: 29357510 Free PMC article.

8

Data Mining and Content Analysis of the Chinese Social Media Platform Weibo During the Early COVID-19 Outbreak: Retrospective Observational Infoveillance Study.

Li J, Xu Q, Cuomo R, Purushothaman V, Mackey T. Li J, et al. Among authors: xu q. JMIR Public Health Surveill. 2020 Apr 21;6(2):e18700. doi: 10.2196/18700. JMIR Public Health Surveill. 2020. PMID: 32293582 Free PMC article.

9

Characterizing Weibo Social Media Posts From Wuhan, China During the Early Stages of the COVID-19 Pandemic: Qualitative Content Analysis.

Xu Q, Shen Z, Shah N, Cuomo R, Cai M, Brown M, Li J, Mackey T. Xu Q, et al. JMIR Public Health Surveill. 2020 Dec 7;6(4):e24125. doi: 10.2196/24125. JMIR Public Health Surveill. 2020. PMID: 33175693 Free PMC article.

10

Impact of COVID-19 on HIV Prevention Access: A Multi-platform Social Media Infodemiology Study.

Xu Q, McMann T, Godinez H, Nali MC, Li J, Cai M, Merenda C, Lee C, Araojo R, Mackey TK. Xu Q, et al. AIDS Behav. 2023 Jun;27(6):1886-1896. doi: 10.1007/s10461-022-03922-z. Epub 2022 Dec 5. AIDS Behav. 2023. PMID: 36471205 Free PMC article.

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