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Specific Inhibition of Hepatic Lactate Dehydrogenase Reduces Oxalate Production in Mouse Models of Primary Hyperoxaluria.
Lai C, Pursell N, Gierut J, Saxena U, Zhou W, Dills M, Diwanji R, Dutta C, Koser M, Nazef N, Storr R, Kim B, Martin-Higueras C, Salido E, Wang W, Abrams M, Dudek H, Brown BD. Lai C, et al. Among authors: wang w. Mol Ther. 2018 Aug 1;26(8):1983-1995. doi: 10.1016/j.ymthe.2018.05.016. Epub 2018 Jun 15. Mol Ther. 2018. PMID: 29914758 Free PMC article.
Inhibition of Glycolate Oxidase With Dicer-substrate siRNA Reduces Calcium Oxalate Deposition in a Mouse Model of Primary Hyperoxaluria Type 1.
Dutta C, Avitahl-Curtis N, Pursell N, Larsson Cohen M, Holmes B, Diwanji R, Zhou W, Apponi L, Koser M, Ying B, Chen D, Shui X, Saxena U, Cyr WA, Shah A, Nazef N, Wang W, Abrams M, Dudek H, Salido E, Brown BD, Lai C. Dutta C, et al. Among authors: wang w. Mol Ther. 2016 Apr;24(4):770-8. doi: 10.1038/mt.2016.4. Epub 2016 Jan 13. Mol Ther. 2016. PMID: 26758691 Free PMC article.
Inhibition of Glycogen Synthase II with RNAi Prevents Liver Injury in Mouse Models of Glycogen Storage Diseases.
Pursell N, Gierut J, Zhou W, Dills M, Diwanji R, Gjorgjieva M, Saxena U, Yang JS, Shah A, Venkat N, Storr R, Kim B, Wang W, Abrams M, Raffin M, Mithieux G, Rajas F, Dudek H, Brown BD, Lai C. Pursell N, et al. Among authors: wang w. Mol Ther. 2018 Jul 5;26(7):1771-1782. doi: 10.1016/j.ymthe.2018.04.023. Epub 2018 Apr 27. Mol Ther. 2018. PMID: 29784585 Free PMC article.
Direct Pharmacological Inhibition of β-Catenin by RNA Interference in Tumors of Diverse Origin.
Ganesh S, Koser ML, Cyr WA, Chopda GR, Tao J, Shui X, Ying B, Chen D, Pandya P, Chipumuro E, Siddiquee Z, Craig K, Lai C, Dudek H, Monga SP, Wang W, Brown BD, Abrams MT. Ganesh S, et al. Among authors: wang w. Mol Cancer Ther. 2016 Sep;15(9):2143-54. doi: 10.1158/1535-7163.MCT-16-0309. Epub 2016 Jul 7. Mol Cancer Ther. 2016. PMID: 27390343 Free PMC article.
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