Wang MK - Search Results

1

Identification of Potent Ebola Virus Entry Inhibitors with Suitable Properties for in Vivo Studies.

Liu H, Tian Y, Lee K, Krishnan P, Wang MK, Whelan S, Mevers E, Soloveva V, Dedic B, Liu X, Cunningham JM. Liu H, et al. Among authors: wang mk. J Med Chem. 2018 Jul 26;61(14):6293-6307. doi: 10.1021/acs.jmedchem.8b00704. Epub 2018 Jul 3. J Med Chem. 2018. PMID: 29920098

2

Critical role for cholesterol in Lassa fever virus entry identified by a novel small molecule inhibitor targeting the viral receptor LAMP1.

Wang MK, Ren T, Liu H, Lim SY, Lee K, Honko A, Zhou H, Dyall J, Hensley L, Gartin AK, Cunningham JM. Wang MK, et al. PLoS Pathog. 2018 Sep 28;14(9):e1007322. doi: 10.1371/journal.ppat.1007322. eCollection 2018 Sep. PLoS Pathog. 2018. PMID: 30265711 Free PMC article.

3

Biochemical Basis for Increased Activity of Ebola Glycoprotein in the 2013-16 Epidemic.

Wang MK, Lim SY, Lee SM, Cunningham JM. Wang MK, et al. Cell Host Microbe. 2017 Mar 8;21(3):367-375. doi: 10.1016/j.chom.2017.02.002. Epub 2017 Feb 23. Cell Host Microbe. 2017. PMID: 28238624 Free PMC article.

4

Species-specific inhibition of RIG-I ubiquitination and IFN induction by the influenza A virus NS1 protein.

Rajsbaum R, Albrecht RA, Wang MK, Maharaj NP, Versteeg GA, Nistal-Villán E, García-Sastre A, Gack MU. Rajsbaum R, et al. Among authors: wang mk. PLoS Pathog. 2012;8(11):e1003059. doi: 10.1371/journal.ppat.1003059. Epub 2012 Nov 29. PLoS Pathog. 2012. PMID: 23209422 Free PMC article.

5

Crystal structure of the TRIM25 B30.2 (PRYSPRY) domain: a key component of antiviral signalling.

D'Cruz AA, Kershaw NJ, Chiang JJ, Wang MK, Nicola NA, Babon JJ, Gack MU, Nicholson SE. D'Cruz AA, et al. Among authors: wang mk. Biochem J. 2013 Dec 1;456(2):231-40. doi: 10.1042/BJ20121425. Biochem J. 2013. PMID: 24015671 Free PMC article.

6

The ubiquitin-specific protease USP15 promotes RIG-I-mediated antiviral signaling by deubiquitylating TRIM25.

Pauli EK, Chan YK, Davis ME, Gableske S, Wang MK, Feister KF, Gack MU. Pauli EK, et al. Among authors: wang mk. Sci Signal. 2014 Jan 7;7(307):ra3. doi: 10.1126/scisignal.2004577. Sci Signal. 2014. PMID: 24399297 Free PMC article.

7

Antagonism of the phosphatase PP1 by the measles virus V protein is required for innate immune escape of MDA5.

Davis ME, Wang MK, Rennick LJ, Full F, Gableske S, Mesman AW, Gringhuis SI, Geijtenbeek TB, Duprex WP, Gack MU. Davis ME, et al. Among authors: wang mk. Cell Host Microbe. 2014 Jul 9;16(1):19-30. doi: 10.1016/j.chom.2014.06.007. Cell Host Microbe. 2014. PMID: 25011105 Free PMC article.

8

Identification of a second binding site on the TRIM25 B30.2 domain.

D'Cruz AA, Kershaw NJ, Hayman TJ, Linossi EM, Chiang JJ, Wang MK, Dagley LF, Kolesnik TB, Zhang JG, Masters SL, Griffin MDW, Gack MU, Murphy JM, Nicola NA, Babon JJ, Nicholson SE. D'Cruz AA, et al. Among authors: wang mk. Biochem J. 2018 Jan 23;475(2):429-440. doi: 10.1042/BCJ20170427. Biochem J. 2018. PMID: 29259080 Free PMC article.

9

Dephosphorylation of the RNA sensors RIG-I and MDA5 by the phosphatase PP1 is essential for innate immune signaling.

Wies E, Wang MK, Maharaj NP, Chen K, Zhou S, Finberg RW, Gack MU. Wies E, et al. Among authors: wang mk. Immunity. 2013 Mar 21;38(3):437-49. doi: 10.1016/j.immuni.2012.11.018. Epub 2013 Mar 14. Immunity. 2013. PMID: 23499489 Free PMC article.

10

Temporal Trends in the Management Practices of Clinically Important Perioperative Atrial Fibrillation After Noncardiac Surgery.

Wang MK, Devereaux PJ, Marcucci M, Lomivorotov V, Sessler DI, Chan MTV, Borges FK, Ofori SN, Paniagua P, Douketis JD, Sigamani A, Parlow JL, Wang CY, Villar JC, Srinathan SK, Szczeklik W, Martínez-Zapata MJ, Malaga G, Sivakumaran S, McIntyre WF, Rodríguez Funes MV, Cruz P, Alvarez-Garcia J, Greiss I, Popova E, Hemels ME, Brandes A, Chow CK, Barnawal SP, Healey JS, Conen D. Wang MK, et al. CJC Open. 2024 Aug 17;6(11):1363-1371. doi: 10.1016/j.cjco.2024.08.003. eCollection 2024 Nov. CJC Open. 2024. PMID: 39582707 Free PMC article.

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