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The c-MYC-BMI1 axis is essential for SETDB1-mediated breast tumourigenesis.
Xiao JF, Sun QY, Ding LW, Chien W, Liu XY, Mayakonda A, Jiang YY, Loh XY, Ran XB, Doan NB, Castor B, Chia D, Said JW, Tan KT, Yang H, Fu XY, Lin DC, Koeffler HP. Xiao JF, et al. Among authors: doan nb. J Pathol. 2018 Sep;246(1):89-102. doi: 10.1002/path.5126. Epub 2018 Aug 3. J Pathol. 2018. PMID: 29926931
SETDB1 accelerates tumourigenesis by regulating the WNT signalling pathway.
Sun QY, Ding LW, Xiao JF, Chien W, Lim SL, Hattori N, Goodglick L, Chia D, Mah V, Alavi M, Kim SR, Doan NB, Said JW, Loh XY, Xu L, Liu LZ, Yang H, Hayano T, Shi S, Xie D, Lin DC, Koeffler HP. Sun QY, et al. Among authors: doan nb. J Pathol. 2015 Mar;235(4):559-70. doi: 10.1002/path.4482. Epub 2014 Dec 18. J Pathol. 2015. PMID: 25404354 Free PMC article.
Genomic and Functional Analysis of the E3 Ligase PARK2 in Glioma.
Lin DC, Xu L, Chen Y, Yan H, Hazawa M, Doan N, Said JW, Ding LW, Liu LZ, Yang H, Yu S, Kahn M, Yin D, Koeffler HP. Lin DC, et al. Cancer Res. 2015 May 1;75(9):1815-27. doi: 10.1158/0008-5472.CAN-14-1433. Epub 2015 Apr 15. Cancer Res. 2015. PMID: 25877876 Free PMC article.
BCL6 promotes glioma and serves as a therapeutic target.
Xu L, Chen Y, Dutra-Clarke M, Mayakonda A, Hazawa M, Savinoff SE, Doan N, Said JW, Yong WH, Watkins A, Yang H, Ding LW, Jiang YY, Tyner JW, Ching J, Kovalik JP, Madan V, Chan SL, Müschen M, Breunig JJ, Lin DC, Koeffler HP. Xu L, et al. Proc Natl Acad Sci U S A. 2017 Apr 11;114(15):3981-3986. doi: 10.1073/pnas.1609758114. Epub 2017 Mar 29. Proc Natl Acad Sci U S A. 2017. PMID: 28356518 Free PMC article.
LNK suppresses interferon signaling in melanoma.
Ding LW, Sun QY, Edwards JJ, Fernández LT, Ran XB, Zhou SQ, Scolyer RA, Wilmott JS, Thompson JF, Doan N, Said JW, Venkatachalam N, Xiao JF, Loh XY, Pein M, Xu L, Mullins DW, Yang H, Lin DC, Koeffler HP. Ding LW, et al. Nat Commun. 2019 May 20;10(1):2230. doi: 10.1038/s41467-019-09711-y. Nat Commun. 2019. PMID: 31110180 Free PMC article.
Genomic and functional characterizations of phosphodiesterase subtype 4D in human cancers.
Lin DC, Xu L, Ding LW, Sharma A, Liu LZ, Yang H, Tan P, Vadgama J, Karlan BY, Lester J, Urban N, Schummer M, Doan N, Said JW, Sun H, Walsh M, Thomas CJ, Patel P, Yin D, Chan D, Koeffler HP. Lin DC, et al. Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):6109-14. doi: 10.1073/pnas.1218206110. Epub 2013 Mar 27. Proc Natl Acad Sci U S A. 2013. PMID: 23536305 Free PMC article.
Growth inhibition of pancreatic cancer cells by histone deacetylase inhibitor belinostat through suppression of multiple pathways including HIF, NFkB, and mTOR signaling in vitro and in vivo.
Chien W, Lee DH, Zheng Y, Wuensche P, Alvarez R, Wen DL, Aribi AM, Thean SM, Doan NB, Said JW, Koeffler HP. Chien W, et al. Among authors: doan nb. Mol Carcinog. 2014 Sep;53(9):722-35. doi: 10.1002/mc.22024. Epub 2013 Mar 8. Mol Carcinog. 2014. PMID: 23475695 Free PMC article.
69 results