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The MELAS mutation m.3243A>G promotes reactivation of fetal cardiac genes and an epithelial-mesenchymal transition-like program via dysregulation of miRNAs.
Meseguer S, Panadero J, Navarro-González C, Villarroya M, Boutoual R, Comi GP, Armengod ME. Meseguer S, et al. Among authors: comi gp. Biochim Biophys Acta Mol Basis Dis. 2018 Sep;1864(9 Pt B):3022-3037. doi: 10.1016/j.bbadis.2018.06.014. Epub 2018 Jun 19. Biochim Biophys Acta Mol Basis Dis. 2018. PMID: 29928977 Free article.
The brain is hypothermic in patients with mitochondrial diseases.
Rango M, Arighi A, Bonifati C, Del Bo R, Comi G, Bresolin N. Rango M, et al. J Cereb Blood Flow Metab. 2014 May;34(5):915-20. doi: 10.1038/jcbfm.2014.38. Epub 2014 Mar 12. J Cereb Blood Flow Metab. 2014. PMID: 24619278 Free PMC article.
Can Intestinal Pseudo-Obstruction Drive Recurrent Stroke-Like Episodes in Late-Onset MELAS Syndrome? A Case Report and Review of the Literature.
Gagliardi D, Mauri E, Magri F, Velardo D, Meneri M, Abati E, Brusa R, Faravelli I, Piga D, Ronchi D, Triulzi F, Peverelli L, Sciacco M, Bresolin N, Comi GP, Corti S, Govoni A. Gagliardi D, et al. Among authors: comi gp. Front Neurol. 2019 Jan 31;10:38. doi: 10.3389/fneur.2019.00038. eCollection 2019. Front Neurol. 2019. PMID: 30766507 Free PMC article.
526 results