Kiso Y - Search Results

1

Deciphering the mechanism of potent peptidomimetic inhibitors targeting plasmepsins - biochemical and structural insights.

Mishra V, Rathore I, Arekar A, Sthanam LK, Xiao H, Kiso Y, Sen S, Patankar S, Gustchina A, Hidaka K, Wlodawer A, Yada RY, Bhaumik P. Mishra V, et al. Among authors: kiso y. FEBS J. 2018 Aug;285(16):3077-3096. doi: 10.1111/febs.14598. Epub 2018 Jul 7. FEBS J. 2018. PMID: 29943906 Free PMC article.

2

Crystal structures of the free and inhibited forms of plasmepsin I (PMI) from Plasmodium falciparum.

Bhaumik P, Horimoto Y, Xiao H, Miura T, Hidaka K, Kiso Y, Wlodawer A, Yada RY, Gustchina A. Bhaumik P, et al. Among authors: kiso y. J Struct Biol. 2011 Jul;175(1):73-84. doi: 10.1016/j.jsb.2011.04.009. Epub 2011 Apr 20. J Struct Biol. 2011. PMID: 21521654 Free PMC article.

3

Structural insights into the activation and inhibition of histo-aspartic protease from Plasmodium falciparum.

Bhaumik P, Xiao H, Hidaka K, Gustchina A, Kiso Y, Yada RY, Wlodawer A. Bhaumik P, et al. Among authors: kiso y. Biochemistry. 2011 Oct 18;50(41):8862-79. doi: 10.1021/bi201118z. Epub 2011 Sep 26. Biochemistry. 2011. PMID: 21928835 Free PMC article.

4

The zymogen of plasmepsin V from Plasmodium falciparum is enzymatically active.

Xiao H, Bryksa BC, Bhaumik P, Gustchina A, Kiso Y, Yao SQ, Wlodawer A, Yada RY. Xiao H, et al. Among authors: kiso y. Mol Biochem Parasitol. 2014 Oct;197(1-2):56-63. doi: 10.1016/j.molbiopara.2014.10.004. Epub 2014 Oct 25. Mol Biochem Parasitol. 2014. PMID: 25447707 Free PMC article.

5

Crystal structures of the histo-aspartic protease (HAP) from Plasmodium falciparum.

Bhaumik P, Xiao H, Parr CL, Kiso Y, Gustchina A, Yada RY, Wlodawer A. Bhaumik P, et al. Among authors: kiso y. J Mol Biol. 2009 May 8;388(3):520-40. doi: 10.1016/j.jmb.2009.03.011. Epub 2009 Mar 11. J Mol Biol. 2009. PMID: 19285084 Free PMC article.

6

Crystal structures of inhibitor complexes of human T-cell leukemia virus (HTLV-1) protease.

Satoh T, Li M, Nguyen JT, Kiso Y, Gustchina A, Wlodawer A. Satoh T, et al. Among authors: kiso y. J Mol Biol. 2010 Aug 27;401(4):626-41. doi: 10.1016/j.jmb.2010.06.052. Epub 2010 Jun 30. J Mol Biol. 2010. PMID: 20600105 Free PMC article.

7

Optimization of plasmepsin inhibitor by focusing on similar structural feature with chloroquine to avoid drug-resistant mechanism of Plasmodium falciparum.

Miura T, Hidaka K, Azai Y, Kashimoto K, Kawasaki Y, Chen SE, de Freitas RF, Freire E, Kiso Y. Miura T, et al. Among authors: kiso y. Bioorg Med Chem Lett. 2014 Apr 1;24(7):1698-701. doi: 10.1016/j.bmcl.2014.02.051. Epub 2014 Mar 3. Bioorg Med Chem Lett. 2014. PMID: 24631188

8

Identification of Highly Potent Human Immunodeficiency Virus Type-1 Protease Inhibitors against Lopinavir and Darunavir Resistant Viruses from Allophenylnorstatine-Based Peptidomimetics with P2 Tetrahydrofuranylglycine.

Hidaka K, Kimura T, Sankaranarayanan R, Wang J, McDaniel KF, Kempf DJ, Kameoka M, Adachi M, Kuroki R, Nguyen JT, Hayashi Y, Kiso Y. Hidaka K, et al. Among authors: kiso y. J Med Chem. 2018 Jun 28;61(12):5138-5153. doi: 10.1021/acs.jmedchem.7b01709. Epub 2018 Jun 11. J Med Chem. 2018. PMID: 29852069

9

Maintaining potent HTLV-I protease inhibition without the P3-cap moiety in small tetrapeptidic inhibitors.

Nguyen JT, Kato K, Kumada HO, Hidaka K, Kimura T, Kiso Y. Nguyen JT, et al. Among authors: kiso y. Bioorg Med Chem Lett. 2011 Mar 15;21(6):1832-7. doi: 10.1016/j.bmcl.2011.01.048. Epub 2011 Jan 15. Bioorg Med Chem Lett. 2011. PMID: 21316958

10

Novel BACE1 inhibitors possessing a 5-nitroisophthalic scaffold at the P2 position.

Hamada Y, Nakanishi T, Suzuki K, Yamaguchi R, Hamada T, Hidaka K, Ishiura S, Kiso Y. Hamada Y, et al. Among authors: kiso y. Bioorg Med Chem Lett. 2012 Jul 15;22(14):4640-4. doi: 10.1016/j.bmcl.2012.05.089. Epub 2012 Jun 1. Bioorg Med Chem Lett. 2012. PMID: 22726930

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

575 results

Search Page

Filters